Evidence map›Paper›PMID 34371985›Full record

SynthesisNutrients2021

Complementary Feeding: Recommendations for the Introduction of Allergenic Foods and Gluten in the Preterm Infant.

Federica Chiale, Elena Maggiora, Arianna Aceti, Nadia Liotto, Alessandra Coscia, Chiara Peila, Maria Elisabetta Baldassarre, Enrico Bertino, Francesco Cresi

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Federica ChialeNeonatal Pathology and Neonatal Intensive Care Unit, Sant'Anna Hospital, City of Health and Science University Hospital of Turin, University of Turin, 10126 Turin, Italy.ORCID 0000-0003-2857-7453
Elena MaggioraNeonatal Pathology and Neonatal Intensive Care Unit, Sant'Anna Hospital, City of Health and Science University Hospital of Turin, University of Turin, 10126 Turin, Italy.
Arianna AcetiNeonatal Intensive Care Unit, AOU Bologna, Department of Medical and Surgical Sciences, University of Bologna, 40138 Bologna, Italy.ORCID 0000-0001-9274-985X
Nadia LiottoFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Neonatal Intensive Care Unit, 20122 Milan, Italy.ORCID 0000-0003-0425-5046
Alessandra CosciaNeonatal Pathology and Neonatal Intensive Care Unit, Sant'Anna Hospital, City of Health and Science University Hospital of Turin, University of Turin, 10126 Turin, Italy.
Chiara PeilaNeonatal Pathology and Neonatal Intensive Care Unit, Sant'Anna Hospital, City of Health and Science University Hospital of Turin, University of Turin, 10126 Turin, Italy.ORCID 0000-0002-0075-5353
Maria Elisabetta BaldassarreDepartment of Human Oncology and Medical Sciences, University "Aldo Moro", 70121 Bari, Italy.ORCID 0000-0003-0590-6664
Enrico BertinoNeonatal Pathology and Neonatal Intensive Care Unit, Sant'Anna Hospital, City of Health and Science University Hospital of Turin, University of Turin, 10126 Turin, Italy.
Francesco CresiNeonatal Pathology and Neonatal Intensive Care Unit, Sant'Anna Hospital, City of Health and Science University Hospital of Turin, University of Turin, 10126 Turin, Italy.ORCID 0000-0002-2139-6855
University of Turin · ITFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · ITUniversity of Bari Aldo Moro · ITUniversity of Bologna · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this systematic review is to analyze the available literature on the introduction of allergenic foods and gluten among preterm infants.

methodsA systematic review of published studies concerning the introduction of gluten and allergenic foods in preterm infants was performed on PubMed and on the Cochrane Library.

resultsOf the 174 PubMed results, 15 papers were considered suitable for the review. A total of 83 records were identified through the Cochrane Library search; eight papers were included in the review. Additional papers were identified from the reference lists of included studies. A secondary search was conducted on the same databases to find recommendations and advice regarding healthy full-term infants that could be translated to preterm infants. Therefore, 59 additional papers were included in the review.

conclusionsCurrent guidelines for the introduction of solid food cannot be directly transposed to preterm infants. Further research is needed to provide evidence-based guidelines regarding weaning in preterm infants. To date, we can suggest that in preterm infants allergenic foods and gluten may be introduced when complementary feeding is started, any time after 4 months of corrected age, avoiding delayed introduction and irrespective of infants' relative risk of developing allergy. Avoiding large amounts of gluten during the first few weeks after gluten introduction and during infancy is advised, despite limited evidence to support this recommendation.

Indexed as

AllergensDietEatingFemaleFood HypersensitivityGlutensHumansInfantInfant FoodInfant, NewbornInfant Nutritional Physiological PhenomenaInfant, PrematureMaleNutrition PolicyAllergensGlutensallergenic foodsceliac diseasecomplementary feedingfood allergyglutenpreterm infantsweaning

Identifiers

PMID34371985
PMCPMC8308791
OpenAlexW3186189503

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.