Evidence map›Paper›PMID 34371977›Full record

ArticleNutrients2021

Daily Rhythm of Fractal Cardiac Dynamics Links to Weight Loss Resistance: Interaction with

Hui-Wen Yang, Marta Garaulet, Peng Li, Cristina Bandin, Chen Lin, Men-Tzung Lo, Kun Hu

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Food Intake According to Clock Gene Polymorphisms: A Systematic Review.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Pooled it
  2. Trial
  3. Observational
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Hui-Wen YangGraduate Institute of Communication Engineering, National Taiwan University, Taipei 10617, Taiwan.
Marta GarauletDivision of Sleep Medicine, Department of Medicine, Harvard Medical School, Boston, MA 02115, USA.ORCID 0000-0002-4066-3509
Peng LiDivision of Sleep and Circadian Disorders, Department of Medicine and Neurology, Brigham and Women's Hospital, Boston, MA 02115, USA.ORCID 0000-0002-4684-4909
Cristina BandinDepartment of Physiology, University of Murcia, IMIB, 30071 Murcia, Spain.
Chen LinInstitute of Translational and Interdisciplinary Medicine, Department of Biomedical Sciences and Engineering, National Central University, Taoyuan 320317, Taiwan.ORCID 0000-0001-6261-8509
Men-Tzung LoInstitute of Translational and Interdisciplinary Medicine, Department of Biomedical Sciences and Engineering, National Central University, Taoyuan 320317, Taiwan.
Kun HuDivision of Sleep and Circadian Disorders, Department of Medicine and Neurology, Brigham and Women's Hospital, Boston, MA 02115, USA.ORCID 0000-0003-0350-3132
Brigham and Women's Hospital · USNational Central University · TWHarvard University · USUniversidad de Murcia · ES

Funding

Integrative Motor Activity Biomarker for the Risk of Alzheimer's RiskRF1AG064312 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI HU, KUN · 2019 to 2019
$3.6M
Fractal motor activity regulation and the risk for Alzheimers disease in middle-to-old aged adultsRF1AG059867 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI HU, KUN · 2018 to 2018
$2.7M
Neuropathology for disrupted multiscale activity control in Alzheimer's diseaseR01AG048108 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI HU, KUN · 2015 to 2018
$1.6M
Autonomous Community of the Region of Murcia through the Seneca Foundation 20795/PI/18Autonomous Community of the Region of Murcia through the Seneca Foundation NIDDK R01DK105072National Science Council 103-2221-E-008-006-MY3National Science Council 103-2321-B-008-003-National Science Council 104-3115-E-008-001-NIH HHS R01AG048108NIH HHS RF1AG059867NIH HHS RF1AG064312The Spanish Government of Investigation, Development and Innovation SAF2017-84135-R
6 · The paper itself

Abstract

The effectiveness of weight loss treatment displays dramatic inter-individual variabilities, even with well-controlled energy intake/expenditure. This study aimed to determine the association between daily rhythms of cardiac autonomic control and weight loss efficiency and to explore the potential relevance to weight loss resistance in humans carrying the genetic variant C at

Indexed as

AdultAutonomic Nervous SystemCase-Control StudiesCircadian RhythmCLOCK ProteinsElectrocardiography, AmbulatoryEnergy IntakeExerciseFemaleFractalsGenotypeHeartHumansMiddle AgedObesityOverweightCLOCK Proteinsautonomic functioncircadian rhythmdietary interventionfractal cardiac dynamicsobesity treatmentweight control

Identifiers

PMID34371977
PMCPMC8308644
OpenAlexW3183595945

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.