Evidence map›Paper›PMID 34371938›Full record

ReviewNutrients2021

A Crosstalk between Diet, Microbiome and microRNA in Epigenetic Regulation of Colorectal Cancer.

Małgorzata Guz, Witold Jeleniewicz, Anna Malm, Izabela Korona-Glowniak

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
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  6. Understanding the intricate interactions between microbiota and host.World journal of experimental medicine · 2025
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  19. Reviewing cancer's biology: an eclectic approach.Journal of the Egyptian National Cancer Institute · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Małgorzata GuzDepartment of Biochemistry and Molecular Biology, Medical University of Lublin, 20-093 Lublin, Poland.ORCID 0000-0001-6783-8017
Witold JeleniewiczDepartment of Biochemistry and Molecular Biology, Medical University of Lublin, 20-093 Lublin, Poland.ORCID 0000-0003-1423-0504
Anna MalmDepartment of Pharmaceutical Microbiology, Medical University of Lublin, 20-093 Lublin, Poland.
Izabela Korona-GlowniakDepartment of Pharmaceutical Microbiology, Medical University of Lublin, 20-093 Lublin, Poland.ORCID 0000-0003-1634-0387
Medical University of Lublin · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A still growing interest between human nutrition in relation to health and disease states can be observed. Dietary components shape the composition of microbiota colonizing our gastrointestinal tract which play a vital role in maintaining human health. There is a strong evidence that diet, gut microbiota and their metabolites significantly influence our epigenome, particularly through the modulation of microRNAs. These group of small non-coding RNAs maintain cellular homeostasis, however any changes leading to impaired expression of miRNAs contribute to the development of different pathologies, including neoplastic diseases. Imbalance of intestinal microbiota due to diet is primary associated with the development of colorectal cancer as well as other types of cancers. In the present work we summarize current knowledge with particular emphasis on diet-microbiota-miRNAs axis and its relation to the development of colorectal cancer.

Indexed as

DietEpigenesis, GeneticGastrointestinal MicrobiomeAnimalsBacteriaBiomarkers, TumorColorectal NeoplasmsDysbiosisGene Expression Regulation, NeoplasticHost-Pathogen InteractionsHumansIntestinesMicroRNAsRisk AssessmentRisk FactorsBiomarkers, TumorMicroRNAscolorectal cancerdietepigeneticgut microbiotagut microbiota-derived metabolitesmiRNAsnutrition

Identifiers

PMID34371938
PMCPMC8308570
OpenAlexW3182908865

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.