Evidence map›Paper›PMID 34371722›Full record

ArticlePharmaceutics2021

In Vitro Metabolism Study of Seongsanamide A in Human Liver Microsomes Using Non-Targeted Metabolomics and Feature-Based Molecular Networking.

Zhexue Wu, Geum Jin Kim, So-Young Park, Jong Cheol Shon, Kwang-Hyeon Liu, Hyukjae Choi

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. The In Vitro Pharmacokinetics of Medicinal Plants: A Review.Pharmaceuticals (Basel, Switzerland) · 2025
    Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zhexue WuMass Spectrometry Based Convergence Research Institute, Kyungpook National University, Daegu 41566, Korea.
Geum Jin KimCollege of Pharmacy and Research Institute of Cell Culture, Yeungnam University, Gyeongsan 38541, Korea.ORCID 0000-0001-8773-3853
So-Young ParkBK21 FOUR Community-Based Intelligent Novel Drug Discovery Education Unit, College of Pharmacy and Research Institute of Pharmaceutical Sciences, Kyungpook National University, Daegu 41566, Korea.
Jong Cheol ShonBK21 FOUR Community-Based Intelligent Novel Drug Discovery Education Unit, College of Pharmacy and Research Institute of Pharmaceutical Sciences, Kyungpook National University, Daegu 41566, Korea.
Kwang-Hyeon LiuMass Spectrometry Based Convergence Research Institute, Kyungpook National University, Daegu 41566, Korea.ORCID 0000-0002-3285-5594
Hyukjae ChoiCollege of Pharmacy and Research Institute of Cell Culture, Yeungnam University, Gyeongsan 38541, Korea.ORCID 0000-0002-7707-4767

Funding

The National Research Foundation of Korea NRF-2019R1A2C1008713
6 · The paper itself

Abstract

Seongsanamide A is a bicyclic peptide with an isodityrosine residue discovered in

Indexed as

Bacillus sp. KCTC 12796BPdrug interactionhigh-resolution mass spectrometrymetabolismseongsanamide A

Identifiers

PMID34371722
PMCPMC8309059

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.