Evidence map›Paper›PMID 34371714›Full record

ArticlePharmaceutics2021

Improved Hygroscopicity and Bioavailability of Solid Dispersion of Red Ginseng Extract with Silicon Dioxide.

Sojeong Jin, Chul Haeng Lee, Dong Yu Lim, Jaehyeok Lee, Soo-Jin Park, Im-Sook Song, Min-Koo Choi

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Sojeong JinCollege of Pharmacy, Dankook University, Cheon-an 31116, Korea.
Chul Haeng LeeCollege of Pharmacy, Dankook University, Cheon-an 31116, Korea.
Dong Yu LimCollege of Pharmacy, Dankook University, Cheon-an 31116, Korea.
Jaehyeok LeeBK21 FOUR Community-Based Intelligent Novel Drug Discovery Education Unit, Vessel-Organ Interaction Research Center (VOICE), Research Institute of Pharmaceutical Sciences, College of Pharmacy, Kyungpook National University, Daegu 41566, Korea.
Soo-Jin ParkCollege of Korean Medicine, Daegu Haany University, Daegu 38610, Korea.
Im-Sook SongBK21 FOUR Community-Based Intelligent Novel Drug Discovery Education Unit, Vessel-Organ Interaction Research Center (VOICE), Research Institute of Pharmaceutical Sciences, College of Pharmacy, Kyungpook National University, Daegu 41566, Korea.ORCID 0000-0002-4564-709X
Min-Koo ChoiCollege of Pharmacy, Dankook University, Cheon-an 31116, Korea.
Dankook University · KRKyungpook National University · KRDaegu Haany University · KR

Funding

Korea government 2017R1C1B5075545National Research Foundation of Korea NRF-2020R1A5A2017323National Research Foundation of Korea NRF-2020R1I1A3074384
6 · The paper itself

Abstract

This study aims to develop a powder formulation for the Korean red ginseng extract (RGE) and to evaluate its in vitro and in vivo formulation characteristics. The solid dispersion of RGE was prepared with hydrophilic carriers using a freeze-drying method. After conducting the water sorption-desorption isothermogram (relative humidity between 30 and 70% RH), differential scanning calorimetry thermal behavior, dissolution test, and intestinal permeation study, a solid dispersion formulation of RGE and silicon dioxide (RGE-SiO

Indexed as

hygroscopicityintestinal permeabilityKorean red ginseng extractoral bioavailabilitysolid dispersion formulation

Identifiers

PMID34371714
PMCPMC8309041
OpenAlexW3181811492

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.