ArticleNeurobiology of disease2021
Neuron-specific mitochondrial oxidative stress results in epilepsy, glucose dysregulation and a striking astrocyte response.
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Article in Neurobiology of disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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21citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
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Who cites it
21 citing papers in PubMed, 34 citations in OpenAlex.
- Morin-Loaded PLGA-Chitosan Nanoparticles Attenuate PTZ-Induced Seizure-Related Behavioral, Biochemical, and Transcriptional Changes in Male Rats.Pharmaceutics · 2026Article
- Disease spectrum of nonconvulsive status epilepticus in children: A study based on clinical subtype characteristics and prognostic stratification.Epileptic disorders : international epilepsy journal with videotape · 2026Article
- Transcriptomic decoding of regional cortical vulnerability to drug-resistant epilepsy using 7T MRI.Communications biology · 2025Article
- Review
- A near-infrared fluorescent probe for dynamic HClO monitoring in epilepsy and high-throughput discovery of natural neuroprotectants.Redox biology · 2025Article
- Seizure and redox rescue in a model of glucose transport deficiency.PLoS computational biology · 2025Article
- Mitochondrial dysfunction in chronic neuroinflammatory diseases (Review).International journal of molecular medicine · 2024Review
- Daytime-Restricted Feeding Ameliorates Oxidative Stress by Increasing NRF2 Transcriptional Factor in the Rat Hippocampus in the Pilocarpine-Induced Acute Seizure Model.Brain sciences · 2023Article
- The Interplay between Mitochondrial Dysfunction and Ferroptosis during Ischemia-Associated Central Nervous System Diseases.Brain sciences · 2023Review
- Neuroprotective and Cardiometabolic Role of Vitamin E: Alleviating Neuroinflammation and Metabolic Disturbance Induced by AlClBiomedicines · 2023Article
- Regulatory Basis of Adipokines Leptin and Adiponectin in Epilepsy: from Signaling Pathways to Glucose Metabolism.Neurochemical research · 2023Review
- TRPM7 kinase mediates hypomagnesemia-induced seizure-related death.Scientific reports · 2023Article
- Therapeutic Strategies to Ameliorate Neuronal Damage in Epilepsy by Regulating Oxidative Stress, Mitochondrial Dysfunction, and Neuroinflammation.Brain sciences · 2023Review
- Neuroprotective effect of piracetam-loaded magnetic chitosan nanoparticles against thiacloprid-induced neurotoxicity in albino rats.Inflammopharmacology · 2023Article
- Neuronal SIRT3 Deletion Predisposes to Female-Specific Alterations in Cellular Metabolism, Memory, and Network Excitability.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- ROS-removing nano-medicine for navigating inflammatory microenvironment to enhance anti-epileptic therapy.Acta pharmaceutica Sinica. B · 2023Article
- Relationship between thyroid hormones and central nervous system metabolism in physiological and pathological conditions.Pharmacological reports : PR · 2022Review
- Reductions in Hydrogen Sulfide and Changes in Mitochondrial Quality Control Proteins Are Evident in the Early Phases of the Corneally Kindled Mouse Model of Epilepsy.International journal of molecular sciences · 2022Article
- Crosstalk between neuroinflammation and oxidative stress in epilepsy.Frontiers in cell and developmental biology · 2022Review
- Can Old Animals Reveal New Targets? The Aging and Degenerating Brain as a New Precision Medicine Opportunity for Epilepsy.Frontiers in neurology · 2022Review
Corrections and comments
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Authors and funding
12 authors at 2 institutions in 2 countries.
Ruth E FultonDepartment of Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Jennifer N Pearson-SmithDepartment of Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA; Division of Geriatric Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Christopher Q HuynhDepartment of Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Timothy FabisiakDepartment of Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Li-Ping LiangDepartment of Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Stefanos AivazidisDepartment of Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Brigit A HighNeuroscience Program, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Georgia BuscagliaNeuroscience Program, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Timothy CorriganDepartment of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Robert ValdezDepartment of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Takahiko ShimizuAging Stress Response Research Project Team, National Center for Geriatrics and Gerontology, Obu, Aichi 474-8511, Japan.
Manisha N PatelDepartment of Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA. Electronic address: Manisha.Patel@ucdenver.edu.
University of Colorado Anschutz Medical Campus · USNational Center for Geriatrics and Gerontology · JP
Funding
ZEBRAFISH TRANSGENIC CORE - ROCKY MOUNTAIN NEUROLOGICAL DISORDERS CORE CENTERP30NS048154 · NINDS · UNIVERSITY OF COLORADO DENVER · PI RIBERA, ANGELES BADELL · 2004 to 2020
$10.1MUniversity of Colorado Aging Training GrantT32AG000279 · NIA · UNIVERSITY OF COLORADO DENVER · PI Kerrie Moreau · 2001 to 2026
$10.1MSUPEROXIDE RADICALS IN SEIZURE-INDUCED NEURONAL DEATHR01NS039587 · NINDS · UNIVERSITY OF COLORADO DENVER · PI PATEL, MANISHA N · 2000 to 2019
$5.9MRedox Control of Seizure-Induced Neuroinflammation.R01NS086423 · NINDS · UNIVERSITY OF COLORADO DENVER · PI PATEL, MANISHA N · 2013 to 2022
$3.0MMitochondrial Mechanisms of Astrogliosis in EpilesyR37NS039587 · NINDS · UNIVERSITY OF COLORADO DENVER · PI MANISHA N PATEL · 2022 to 2026
$2.8MNIA NIH HHS T32 AG000279NINDS NIH HHS P30 NS048154NINDS NIH HHS R01 NS039587NINDS NIH HHS R01 NS086423NINDS NIH HHS R37 NS039587
Abstract
Mitochondrial superoxide (O
Indexed as
MitochondriaNeuronsOxidative StressAnimalsAstrocytesBehavior, AnimalElectroencephalographyEpilepsyGlial Fibrillary Acidic ProteinGlucose Metabolism DisordersMiceMice, Inbred C57BLMice, KnockoutMotor ActivityPrimary Cell CultureRatsGlial Fibrillary Acidic Proteinglial fibrillary astrocytic protein, mouseSuperoxide DismutaseSuperoxide Dismutase 2Superoxides
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.