Evidence map›Paper›PMID 34370900›Full record

ArticleEuropean journal of neurology2022

A full year of the COVID-19 pandemic with two infection waves and its impact on ischemic stroke patient care in Germany.

Daniel Richter, Jens Eyding, Ralph Weber, Dirk Bartig, Armin Grau, Werner Hacke, Christos Krogias

Open access · hybridAbstract read
In one paragraph

Article in European journal of neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 44 citations in OpenAlex.

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  15. Stroke admissions during the COVID-19 pandemic: a single-center retrospective analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022
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  18. Time Metrics in Acute Ischemic Stroke Care During the Second and First Wave of COVID 19 Pandemic: A Tertiary Care Center Experience from South India.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Daniel RichterDepartment of Neurology, St. Josef Hospital Bochum, Ruhr University Bochum, Bochum, Germany.
Jens EydingMedical Faculty, Ruhr University Bochum, Bochum, Germany.
Ralph WeberMedical Faculty, Ruhr University Bochum, Bochum, Germany.ORCID 0000-0002-5486-7027
Dirk BartigDepartment of Neurology, St. Josef Hospital Bochum, Ruhr University Bochum, Bochum, Germany.
Armin GrauDepartment of Neurology, Hospital of the City Ludwigshafen, Ludwigshafen, Germany.
Werner HackeDepartment of Neurology, University of Heidelberg, Heidelberg, Germany.
Christos KrogiasDepartment of Neurology, St. Josef Hospital Bochum, Ruhr University Bochum, Bochum, Germany.ORCID 0000-0003-2965-4051
St. Josef-Hospital · DEAlfried Krupp Hospital · DEGemeinschaftskrankenhaus Herdecke · DEHeidelberg University · DEKlinikum Ludwigshafen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeMany countries worldwide, including Germany, reported that the first wave of the coronavirus disease 2019 (COVID-19) pandemic in early 2020 influenced the care of acute ischemic stroke (AIS) patients, but data are lacking for further pandemic wave periods.

methodsWe conducted a nationwide, retrospective, cross-sectional study of all hospitalized patients with the main diagnosis of AIS in 2019 and 2020. Primary outcomes were the number of hospitalizations for AIS, the application of stroke unit care, intravenous thrombolysis (IVT), and mechanical thrombectomy (MT), as well as the in-hospital mortality during the different pandemic periods in 2020 compared to the corresponding periods in 2019. Secondarily, we analyzed differences in outcomes between patients with and without concurrent COVID-19.

resultsWe included 429,841 cases with AIS, of which 1268 had concurrent COVID-19. Hospitalizations for AIS declined during both pandemic wave periods in 2020 (first wave: -10.9%, second wave: -4.6%). MT rates were consistently higher throughout 2020 compared to 2019, whereas the IVT rate dropped during the second wave period (16.0% vs. 17.0%, p < 0.001). AIS patients with concurrent COVID-19 frequently received recanalization treatments, with an overall MT rate of 8.4% and IVT rate of 15.9%. The in-hospital mortality was high (22.8% vs. 7.5% in noninfected AIS patients, p < 0.001).

conclusionsThese findings demonstrate a smaller decline in hospitalizations for AIS in the more severe second wave of the COVID-19 pandemic. AIS patients with and without concurrent COVID-19 who did seek acute care continued to receive recanalization treatments in Germany.

Indexed as

Brain IschemiaCOVID-19Ischemic StrokeStrokeCross-Sectional StudiesGermanyHumansPandemicsPatient CareRetrospective StudiesSARS-CoV-2ThrombectomyThrombolytic TherapyTreatment OutcomeCOVID-19Germanystrokethrombectomythrombolysis

Identifiers

PMID34370900
PMCPMC8444778
OpenAlexW3192870742

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.