Evidence map›Paper›PMID 34370576›Full record

ArticleAntimicrobial agents and chemotherapy2021

Extensively Drug-Resistant Acinetobacter baumannii Nosocomial Pneumonia Successfully Treated with a Novel Antibiotic Combination.

Noor Zaidan, J Patrik Hornak, David Reynoso

Open access · greenAbstract readCase Reports
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.

  1. Pooled it
  2. Antimicrobial agents and chemotherapy · 2025
    Review
  3. Article
  4. Review
  5. Sulbactam for carbapenem-resistantJAC-antimicrobial resistance · 2025
    Review
  6. Sulbactam-Durlobactam: A Novel Antibiotic Combination for the Treatment ofThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2025
    Review
  7. Successful Treatment of OXA-23Infection and drug resistance · 2025
    Article
  8. Article
  9. Article
  10. Antibiotic Treatment of Carbapenem-ResistantAntibiotics (Basel, Switzerland) · 2024
    Review
  11. Article
  12. Treatment of infections caused by carbapenem-resistantFrontiers in cellular and infection microbiology · 2024
    Review
  13. Review
  14. In Vivo Emergence of Pandrug-ResistantOpen forum infectious diseases · 2023
    Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Navigating Available Treatment Options for Carbapenem-Resistant Acinetobacter baumannii-calcoaceticus Complex Infections.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Noor ZaidanDepartment of Pharmacy, University of Texas Medical Branch at Galveston, Galveston, Texas, USA.
J Patrik HornakDivision of Infectious Diseases, Department of Internal Medicine, University of Texas Medical Branch at Galveston, Galveston, Texas, USA.ORCID 0000-0002-7644-6880
David ReynosoDivision of Infectious Diseases, Department of Internal Medicine, University of Texas Medical Branch at Galveston, Galveston, Texas, USA.
The University of Texas Medical Branch at Galveston · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extremely drug-resistant (XDR) Acinetobacter baumannii causes challenging nosocomial infections. We report the case of a patient with XDR A. baumannii pneumonia and septic shock successfully treated with cefiderocol and a novel antibiotic obtained via expanded access protocol. With focused research and drug development efforts, the poor outcomes associated with these infections may be mitigated.

Indexed as

Acinetobacter baumanniiAcinetobacter InfectionsCross InfectionHealthcare-Associated PneumoniaPharmaceutical PreparationsAnti-Bacterial AgentsDrug Resistance, Multiple, BacterialHumansMicrobial Sensitivity TestsAnti-Bacterial AgentsPharmaceutical PreparationsAcinetobacter baumaniiantibiotic resistanceantimicrobial agentsbeta-lactamasesbeta-lactamsdurlobactamGram-negative bacteriaGram-negative resistancenosocomial infectionsnovel antibioticssulbactam-durlobactam

Identifiers

PMID34370576
PMCPMC8522738
OpenAlexW3190992299

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.