Evidence map›Paper›PMID 34370574›Full record

ArticleAntimicrobial agents and chemotherapy2021

Activity of Imipenem-Relebactam against Multidrug- and Extensively Drug-Resistant Burkholderia cepacia Complex and Burkholderia gladioli.

Scott A Becka, Elise T Zeiser, John J LiPuma, Krisztina M Papp-Wallace

Open access · greenAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 24 citations in OpenAlex.

  1. Case Commentary: When susceptibility is not enough in recurrentAntimicrobial agents and chemotherapy · 2026
    Article
  2. Article
  3. In vitro susceptibility ofNew microbes and new infections · 2025
    Review
  4. Revisiting the Metallo-International journal of microbiology · 2025
    Review
  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. The Class A β-Lactamase Produced byAntibiotics (Basel, Switzerland) · 2022
    Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Scott A BeckaResearch Service, VA Northeast Healthcare System, Cleveland, Ohio, USA.
Elise T ZeiserResearch Service, VA Northeast Healthcare System, Cleveland, Ohio, USA.
John J LiPumaDepartment of Pediatrics, University of Michigan Medical School, Ann Arbor, Michigan, USA.ORCID 0000-0003-4033-7794
Krisztina M Papp-WallaceResearch Service, VA Northeast Healthcare System, Cleveland, Ohio, USA.ORCID 0000-0002-9976-7898
Northeast Health · USUniversity of Michigan · US

Funding

Targeting Burkholderial β-lactamases: Structure, function, and regulationI01BX002872 · VA · LOUIS STOKES CLEVELAND VA MEDICAL CENTER · PI DONSKEY, CURTIS, PAPP-WALLACE, KRISZTINA MARGARET · 2016 to 2023
–
BLRD VA I01 BX002872Cystic Fibrosis Foundation (CF Foundation)U.S. Department of Veterans Affairs (VA) BX002872
6 · The paper itself

Abstract

The Burkholderia cepacia complex (Bcc) and Burkholderia gladioli are opportunistic pathogens that most commonly infect persons with cystic fibrosis or compromised immune systems. Members of the

Indexed as

Burkholderia cepacia complexBurkholderia gladioliAnti-Bacterial AgentsAzabicyclo Compoundsbeta-LactamasesBurkholderiaDrug Resistance, Multiple, BacterialImipenemMicrobial Sensitivity TestsAnti-Bacterial AgentsAzabicyclo Compoundsbeta-LactamasesImipenemrelebactamantibiotic resistanceavibactamBurkholderiacarbapenemaseceftazidimeimipenemPenArelebactamβ-lactamβ-lactamase inhibitorβ-lactamases

Identifiers

PMID34370574
PMCPMC8522746
OpenAlexW3188638063

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.