Evidence map›Paper›PMID 34370572›Full record

ArticleAntimicrobial agents and chemotherapy2021

Imipenem-Relebactam Susceptibility and Genotypic Characteristics of Carbapenem-Resistant

Sam Horwich-Scholefield, Tyler Lloyd, Vici Varghese, Emily Yette, Sandra Huang, Mark Pandori

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Epidemiology of carbapenem-resistant organisms in Alameda County, California, 2019-2021.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2024
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sam Horwich-ScholefieldAlameda County Public Health Departmentgrid.457032.7, San Leandro, California, USA.ORCID 0000-0001-5921-7536
Tyler LloydAlameda County Public Health Laboratory, Oakland, California, USA.
Vici VargheseAlameda County Public Health Laboratory, Oakland, California, USA.
Emily YetteAlameda County Public Health Departmentgrid.457032.7, San Leandro, California, USA.
Sandra HuangAlameda County Public Health Departmentgrid.457032.7, San Leandro, California, USA.
Mark PandoriNevada State Public Health Laboratory, Reno, Nevada, USA.

Funding

Merck (Merck & Co., Inc.) 58488
6 · The paper itself

Abstract

Laboratories submit all carbapenem-resistant Enterobacter, Escherichia coli, and Klebsiella species to the Alameda County Public Health Department (ACPHD). ACPHD evaluated 75 isolates submitted during 9 months for susceptibility to imipenem-relebactam (I-R) and, using whole-genome sequencing, identified β-lactamase genes. Of 60 (80%) isolates susceptible to I-R, 8 (13%) had detectable carbapenemase genes, including 4 KPC, two NDM, and two OXA-48-like; we described the relationship between the presence of β-lactamase resistance genes and susceptibility to I-R.

Indexed as

CarbapenemsDrug Resistance, BacterialGammaproteobacteriaImipenemAnti-Bacterial AgentsAzabicyclo CompoundsBacterial Proteinsbeta-LactamasesMicrobial Sensitivity TestsAnti-Bacterial AgentsAzabicyclo CompoundsBacterial Proteinsbeta-LactamasesCarbapenemsImipenemrelebactamcarbapenem resistanceimipenem-relebactamNDMwhole-genome sequencingβ-lactamase inhibitor

Identifiers

PMID34370572
PMCPMC8522770

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.