Evidence map›Paper›PMID 34370561›Full record

ReviewJournal of bacteriology2021

Let Me Upgrade You: Impact of Mobile Genetic Elements on Enterococcal Adaptation and Evolution.

Cydney N Johnson, Emma K Sheriff, Breck A Duerkop, Anushila Chatterjee

Open access · greenAbstract readReview
In one paragraph

Review in Journal of bacteriology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Novel transposon TnMicrobial genomics · 2026
    Article
  6. Article
  7. Novel transposon TnmedRxiv : the preprint server for health sciences · 2026
    Article
  8. A One-Health Perspective onEnvironmental health insights · 2026
    Review
  9. Plasmid-linked virulence genes and high-level gentamicin resistance inJournal of conservative dentistry and endodontics · 2026
    Article
  10. Synergistic interactions betweenProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  11. Hidden diversity inMicrobiology spectrum · 2025
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Development of an RT-LAMP Assay for DetectingDiagnostics (Basel, Switzerland) · 2025
    Article
  18. Review
  19. Development of an infant colon simulatingMicrobiology spectrum · 2024
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Cydney N JohnsonDepartment of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, Colorado, USA.
Emma K SheriffDepartment of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, Colorado, USA.
Breck A DuerkopDepartment of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, Colorado, USA.ORCID 0000-0003-4030-9822
Anushila ChatterjeeDepartment of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, Colorado, USA.ORCID 0000-0002-8023-3925
University of Colorado Denver · US

Funding

Mechanistic basis of bacteriophages for the decolonization of vancomycin resistant enterococci in the intestine.R01AI141479 · NIAID · UNIVERSITY OF COLORADO DENVER · PI DUERKOP, BRECK A · 2018 to 2025
$4.4M
Molecular Pathogenesis of Infectious DiseasesT32AI052066 · NIAID · UNIVERSITY OF COLORADO DENVER · PI VAN DYK, LINDA F. · 2002 to 2022
$2.3M
Molecular mechanisms of lytic bacteriophage infection of enterococciF31AI157050 · NIAID · UNIVERSITY OF COLORADO DENVER · PI JOHNSON, CYDNEY N · 2021 to 2022
$42k
NIAID NIH HHS F31 AI157050NIAID NIH HHS R01 AI141479NIAID NIH HHS R01AI141479NIAID NIH HHS T32 AI052066
6 · The paper itself

Abstract

Enterococci are Gram-positive bacteria that have evolved to thrive as both commensals and pathogens, largely due to their accumulation of mobile genetic elements via horizontal gene transfer (HGT). Common agents of HGT include plasmids, transposable elements, and temperate bacteriophages. These vehicles of HGT have facilitated the evolution of the enterococci, specifically Enterococcus faecalis and Enterococcus faecium, into multidrug-resistant hospital-acquired pathogens. On the other hand, commensal strains of

Indexed as

Biological EvolutionCRISPR-Cas SystemsEnterococcus faecalisEnterococcus faeciumInterspersed Repetitive Sequencesantibiotic resistanceCRISPRenterococcihorizontal gene transfermobile genetic elementsphagepheromone-responsive plasmidtransposonvirulence

Identifiers

PMID34370561
PMCPMC8508098
OpenAlexW3191036774

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.