Evidence map›Paper›PMID 34370553›Full record

ArticleMolecular and cellular biology2021

Impaired Skin Barrier Function Due to Reduced ω-

Koki Nojiri, Shuhei Fudetani, Ayami Arai, Takuya Kitamura, Takayuki Sassa, Akio Kihara

Open access · greenAbstract read
In one paragraph

Article in Molecular and cellular biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Koki Nojiri *Laboratory of Biochemistry, Faculty of Pharmaceutical Sciences, Hokkaido Universitygrid.39158.36, Sapporo, Japan.
Shuhei Fudetani *Laboratory of Biochemistry, Faculty of Pharmaceutical Sciences, Hokkaido Universitygrid.39158.36, Sapporo, Japan.
Ayami Arai *Laboratory of Biochemistry, Faculty of Pharmaceutical Sciences, Hokkaido Universitygrid.39158.36, Sapporo, Japan.
Takuya KitamuraLaboratory of Biochemistry, Faculty of Pharmaceutical Sciences, Hokkaido Universitygrid.39158.36, Sapporo, Japan.
Takayuki SassaLaboratory of Biochemistry, Faculty of Pharmaceutical Sciences, Hokkaido Universitygrid.39158.36, Sapporo, Japan.ORCID 0000-0003-3145-9829
Akio KiharaLaboratory of Biochemistry, Faculty of Pharmaceutical Sciences, Hokkaido Universitygrid.39158.36, Sapporo, Japan.ORCID 0000-0001-5889-0788
Hokkaido University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sjögren-Larsson syndrome (SLS) is an inherited neurocutaneous disorder whose causative gene encodes the fatty aldehyde dehydrogenase ALDH3A2. To date, the detailed molecular mechanism of the skin pathology of SLS has remained largely unclear. We generated double-knockout (DKO) mice for

Indexed as

Aldehyde DehydrogenaseAldehyde OxidoreductasesAldehydesAnimalsCell DifferentiationCeramidesDisease Models, AnimalEpidermisFatty AcidsFemaleKeratinocytesMaleMiceMice, Inbred C57BLMice, KnockoutSjogren-Larsson SyndromeAldehyde DehydrogenaseAldehyde OxidoreductasesAldehydesAldh3a1 protein, mouseCeramidesFatty Acidsfatty aldehydelong-chain-aldehyde dehydrogenasealdehyde dehydrogenaseceramideichthyosislipidlong-chain baseSjögren-Larsson syndromeskinsphingolipid

Identifiers

PMID34370553
PMCPMC8462457
OpenAlexW3191150999

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.