Evidence map›Paper›PMID 34370510›Full record

ArticleInfection and immunity2021

Immunoreactive Protein Repertoires of Ehrlichia chaffeensis and E. canis Reveal the Dominance of Hypothetical Proteins and Conformation-Dependent Antibody Epitopes.

Tian Luo, Jignesh G Patel, Xiaofeng Zhang, David H Walker, Jere W McBride

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Infection and immunity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.4field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Veterinary sciences · 2024
    Review
  4. Immuno- and expression analysis ofFrontiers in veterinary science · 2024
    Article
  5. Review
  6. Article
  7. Antibody reactive immunomes ofFrontiers in cellular and infection microbiology · 2023
    Article
  8. Type 1 secretion system and effectors in Rickettsiales.Frontiers in cellular and infection microbiology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Tian Luo *Department of Pathology, University of Texas Medical Branch, Galveston, Texas, USA.ORCID 0000-0003-4360-3429
Jignesh G Patel *Department of Pathology, University of Texas Medical Branch, Galveston, Texas, USA.
Xiaofeng ZhangDepartment of Pathology, University of Texas Medical Branch, Galveston, Texas, USA.
David H WalkerDepartment of Pathology, University of Texas Medical Branch, Galveston, Texas, USA.
Jere W McBrideDepartment of Pathology, University of Texas Medical Branch, Galveston, Texas, USA.ORCID 0000-0003-3335-1539
The University of Texas Medical Branch at Galveston · US

Funding

NCEZID CDC HHS U01 CK000512
6 · The paper itself

Abstract

The immunomes of Ehrlichia chaffeensis and Ehrlichia canis have recently been revised to include immunodominant hypothetical proteins with conformational antibody epitopes. In this study, we examined 216 E. chaffeensis and 190 E. canis highly antigenic proteins according to ANTIGENpro and also performed a genome-wide hypothetical protein analysis (E. chaffeensis

Indexed as

Antibodies, BacterialComputational BiologyEhrlichia canisEhrlichia chaffeensisEnzyme-Linked Immunosorbent AssayEpitopesHumansProtein ConformationAntibodies, BacterialEpitopesantibodyconformation-dependentEhrlichiaepitopeimmunoreactive

Identifiers

PMID34370510
PMCPMC8519286
OpenAlexW3187724435

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.