Evidence map›Paper›PMID 34370509›Full record

ArticleInfection and immunity2021

Plasmacytoid Dendritic Cell-Derived Type I Interferon Is Involved in Helicobacter pylori Infection-Induced Differentiation of Schlafen 4-Expressing Myeloid-Derived Suppressor Cells.

Xiaodan Xiang, Yaping Wu, Hongwei Li, Cun Li, Lu Yan, Qian Li

Open access · greenAbstract read
In one paragraph

Article in Infection and immunity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 18 citations in OpenAlex.

  1. Myeloid-derived suppressor cells modulation in the context of tumor microenvironment for gastric cancer.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025
    Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. The intersection ofFrontiers in cellular and infection microbiology · 2025
    Review
  7. iScience · 2024
    Article
  8. Review
  9. Review
  10. Review
  11. [CanThe Korean journal of helicobacter and upper gastrointestinal research · 2023
    Article
  12. Article
  13. Effects ofFrontiers in immunology · 2022
    Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Xiaodan XiangDepartment of Gastroenterology, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Yaping WuDepartment of Gastroenterology, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Hongwei LiDepartment of Gastroenterology, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Cun LiDepartment of Gastroenterology, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Lu YanDepartment of Gastroenterology, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Qian LiDepartment of Gastroenterology, Xiangya Hospital, Central South University, Changsha, Hunan, China.ORCID 0000-0002-3675-7131
Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During chronic infection with Helicobacter pylori, Schlafen 4-expressing myeloid-derived suppressor cells (SLFN4

Indexed as

Helicobacter pyloriAnimalsCarrier ProteinsCell DifferentiationDendritic CellsHelicobacter InfectionsInterferon Regulatory Factor-7Interferon Type IMiceMice, Inbred C57BLMyeloid-Derived Suppressor CellsMyeloid Differentiation Factor 88Promoter Regions, GeneticToll-Like Receptor 9Carrier ProteinsInterferon Regulatory Factor-7Interferon Type IIrf7 protein, mouseMyd88 protein, mouseMyeloid Differentiation Factor 88schlafen-4 protein, mouseTlr9 protein, mouseToll-Like Receptor 9Helicobacter pyloriIFN-αplasmacytoid dendritic cellsSLFN4+ MDSC

Identifiers

PMID34370509
PMCPMC8519294
OpenAlexW3191397561

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.