Evidence map›Paper›PMID 34370068›Full record

ArticleActa neuropathologica2021

Epigenetic and gene expression changes of neuronal cells from MSA patients are pronounced in enzymes for cell metabolism and calcium-regulated protein kinases.

Laura de Boni, Gilles Gasparoni, Anna Welle, Sascha Tierling, Ina Schmitt, Jörn Walter, Jochen Walter, Ullrich Wüllner

Open access · hybridAbstract readLetter
In one paragraph

Article in Acta neuropathologica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Laura de BoniDepartment of Neurology, University Hospital Bonn, Venusberg-Campus 1, Bonn, Germany. laura.deboni@ukbonn.de.ORCID 0000-0001-7785-482X
Gilles GasparoniDepartment of Genetics/Epigenetics, Saarland University, Campus Saarbrücken, Building A2 4, Saarbrücken, Germany.
Anna WelleDepartment of Genetics/Epigenetics, Saarland University, Campus Saarbrücken, Building A2 4, Saarbrücken, Germany.
Sascha TierlingDepartment of Genetics/Epigenetics, Saarland University, Campus Saarbrücken, Building A2 4, Saarbrücken, Germany.
Ina SchmittDepartment of Neurology, University Hospital Bonn, Venusberg-Campus 1, Bonn, Germany.
Jörn WalterDepartment of Genetics/Epigenetics, Saarland University, Campus Saarbrücken, Building A2 4, Saarbrücken, Germany.
Jochen WalterDepartment of Neurology, University Hospital Bonn, Venusberg-Campus 1, Bonn, Germany.
Ullrich WüllnerDepartment of Neurology, University Hospital Bonn, Venusberg-Campus 1, Bonn, Germany.
University Hospital Bonn · DESaarland University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CalciumEpigenesis, GeneticHumansMultiple System AtrophyOccipital LobeProtein KinasesCalciumProtein Kinases

Identifiers

PMID34370068
PMCPMC8423633
OpenAlexW3189806226

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.