Evidence map›Paper›PMID 34369915›Full record

ArticleThe Journal of cardiovascular nursing

Reported Signs, Symptoms, and Diagnostic Tests Before Cardiotoxicity Among Women With Breast Cancer: A Pilot Study.

Mina Attin, Karen Reifenstein, Sakshi Mehta, Kimberly Arcoleo, C D Lin, Eugene Storozynsky

Abstract read
In one paragraph

Article in The Journal of cardiovascular nursing. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mina Attin
Karen Reifenstein
Sakshi Mehta
Kimberly Arcoleo
C D Lin
Eugene Storozynsky

Funding

The Research Infrastructure Core of SDSU HealthLINK Center for Transdisciplinary Health Disparities ResearchU54MD012397 · NIMHD · SAN DIEGO STATE UNIVERSITY · PI Elva M Arredondo · 2018 to 2026
$39.0M
Building Capacity and Infrastructure for Population Health and Health Disparities Research at San Diego State UniversityS21MD010690 · NIMHD · SAN DIEGO STATE UNIVERSITY · PI AYALA, GUADALUPE X, CASTILLO, JOSE E · 2016 to 2020
$10.0M
NIMHD NIH HHS S21 MD010690NIMHD NIH HHS U54 MD012397
6 · The paper itself

Abstract

backgroundCardiotoxicity after cancer treatment is a potentially preventable life-threatening complication among women with breast cancer. There is no algorithm to identify women with breast cancer at risk of cardiotoxicity.

objectivesWe quantified signs and symptoms as well as selected laboratory values among women with breast cancer who developed cardiotoxicity.

methodsThe clinical characteristics (n = 15) were collected from electronic health records. Spearman correlation coefficients and a nonparametric statistical test were used to analyze data.

resultsSignificant statistical differences were detected in the laboratory values comparing the first and second half of 6 months before cardiotoxicity including alanine aminotransferase (U/L) (30.67 ± 26.27 and 42.31 ± 35.65, respectively; P = .03, Cohen's d = 0.37). A negative correlation was found between estimated glomerular filtration rate and new onset of more than 1 sign or symptom (Spearman's ρ = -0.5, P = .06).

conclusionsInvestigating clinical characteristics before cardiotoxicity may determine the mechanism(s) and identify high-risk patients.

Indexed as

Breast NeoplasmsCardiotoxicityDiagnostic Tests, RoutineFemaleHumansPilot Projects

Identifiers

PMID34369915
PMCPMC9070097

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.