ArticleAnatolian journal of cardiology2021
Left ventricular characteristics of noncompaction phenotype patients with good ejection fraction measured with cardiac magnetic resonance.
Article in Anatolian journal of cardiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 11 citations in OpenAlex.
- Cardiac magnetic resonance imaging predictors of outcomes in noncompaction cardiomyopathy: A systematic review and meta-analysis.The international journal of cardiovascular imaging · 2026Review
- Novel, Contrast Echocardiography-Based Trabeculation Quantification Method in the Diagnosis of Left Ventricular Excessive Trabeculation.Journal of imaging · 2026Article
- New Solution for Segmental Assessment of Left Ventricular Wall Thickness, Using Anatomically Accurate and Highly Reproducible Automated Cardiac MRI Software.Journal of imaging · 2025Article
- Comparison of Imaging Modalities for Left Ventricular Noncompaction Morphology.Journal of imaging · 2025Article
- Inherited Hypertrabeculation? Genetic and Clinical Insights in Blood Relatives of Genetically Affected Left Ventricular Excessive Trabeculation Patients.Life (Basel, Switzerland) · 2025Article
- Electrocardiogram Features of Left Ventricular Excessive Trabeculation with Preserved Cardiac Function in Light of Cardiac Magnetic Resonance and Genetics.Journal of clinical medicine · 2024Article
- Genetic, clinical and imaging implications of a noncompaction phenotype population with preserved ejection fraction.Frontiers in cardiovascular medicine · 2024Article
- The effect of excessive trabeculation on cardiac rotation-A multimodal imaging study.PloS one · 2024Article
- Myocardial Mechanics and Associated Valvular and Vascular Abnormalities in Left Ventricular Noncompaction Cardiomyopathy.Journal of clinical medicine · 2023Review
- Article
- Pathophysiology of Non-compaction Remains Enigmatic.Anatolian journal of cardiology · 2022Article
- Reply to letter to the editor: "Pathophysiology of Non-compaction Remains Enigmatic".Anatolian journal of cardiology · 2022Article
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Authors and funding
11 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveWe describe left ventricular (LV) volumes, myocardial and trabeculated muscle mass and strains with Cardiac magnetic resonance of a large cohort (n=81) who fulfilled the morphologic criteria of left ventricular noncompaction (LVNC) and had good ejection fraction (EF >55%) and compare them with healthy controls (n=81). Male and female patients were compared to matched controls and to each other. We also investigated the LV trabeculated muscle mass cutoff in male and female patients with LVNC.
methods81 participants with LVNC and 81 healthy controls were included. Male and female patients were compared to matched controls and to each other. We also investigated the left ventricular trabeculated muscle mass cut-off in male and female LVNC patients.
resultsThe LV parameters of the LVNC population were normal, but they had significantly higher volumes, myocardial and trabeculated muscle mass, and a significantly smaller EF than the controls. Similar differences were observed after stratifying by sex. The optimal LV trabeculated muscle mass cutoffs were 25.8 g/m2 in men (area under the curve: 0.81) and 19.0 g/m2 in women (area under the curve: 0.87). The patients had normal global strains but a significantly worse global circumferential strain (patients vs controls: -29.9±4.9 vs. -35.8±4.7%, p<0.05) and significantly higher circumferential mechanical dispersion than the controls (patients vs. controls: 7.6±4.2 vs. 6.1±2.8%; p<0.05). No disease-related strain differences were noted between men and women.
conclusionThe LV functional and strain characteristics of the LVNC cohort differed significantly from those of healthy participants; this might be caused by increased LV trabeculation, and its clinical relevance might be questionable. The LV trabeculated muscle mass was very different between men and women; thus, the use of sex-specific morphologic diagnostic criteria should be considered.
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