Evidence map›Paper›PMID 34369873›Full record

ArticleBlood transfusion = Trasfusione del sangue2021

A nationwide survey of clinical use of blood in Italy.

Giuseppina Facco, Francesco Bennardello, Francesco Fiorin, Claudia Galassi, Chiara Monagheddu, Pierluigi Berti, SIMTI Study Group for Clinical Use of Blood in Italy

Open access · greenAbstract read
In one paragraph

Article in Blood transfusion = Trasfusione del sangue, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.3field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Giuseppina FaccoItalian Society of Transfusion Medicine and Immunohaematology, Rome, Italy.
Francesco BennardelloImmunohaematology and Transfusion Medicine Centre, Provincial Health Authority n. 7, Ragusa - "R. Guzzardi" Hospital, Vittoria, Italy.
Francesco FiorinTransfusion Department, Provincial Health Authority of Vicenza, ULSS 8 Berica, Italy.
Claudia GalassiUnit of Clinical Epidemiology "Città della Salute e della Scienza di Torino" University Hospital and CPO Piedmont, Turin, Italy.
Chiara MonaghedduUnit of Clinical Epidemiology "Città della Salute e della Scienza di Torino" University Hospital and CPO Piedmont, Turin, Italy.
Pierluigi BertiImmunohaematology and Transfusion Medicine, "Umberto Parini" Hospital, Aosta, Italy.
SIMTI Study Group for Clinical Use of Blood in Italy
Italian Society of Physiotherapy · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn Italy, as in many developed countries, a decline in blood component (BC) consumption, especially red blood cells (RBC), has been described, but not studied at a national level. We, therefore, designed a nationwide survey to determine the main features of BC recipients and obtain a picture of the clinical use of BC for the first time in Italy, in order to understand BC demands better and identify specific fields in which to apply Patient Blood Management (PBM). MATERIAL AND

methodsA nationwide survey of all Italian Blood Establishments working as Hospital Blood Banks (HBB) was performed. Data were collected through an online report form recording information on the number and geographic area of the responding HBB, year of birth and sex of the BC recipients, and clinical indications for every unit of RBC, platelets and plasma transfused in a 24-hour period.

resultsOn the survey date, 153/237 (64.5%) of the HBB returned 4,356 forms, reporting 7,523 transfusions. The median and mean ages of the recipients were 73 (range, 0-106) and 67.5 years, respectively; 33.0% were >80 years old and 64.9% >65 years old, with no relevant differences between males and females. Overall, 6,309 RBC units were transfused to 3,850 recipients, 66.7% of them for a medical indication and 32.4% for a surgical indication. The commonest medical indication was acquired, non-cancer-related anaemia and more than 30% of the transfusions occurred in the Emergency Department. Five hundred and sixty platelet transfusions were given to 520 recipients, 62.7% of them for prophylaxis and 28.6% for bleeding before or during an invasive procedure or surgery or for thrombocytopenia. One hundred and ninety-four patients received 654 units of plasma, 71.1% of which were for therapeutic purposes in bleeding patients. DISCUSSION: We collected a picture of blood transfusion epidemiology in Italy. The data suggest that future PBM plans should be focused on medical anaemia especially in the setting of Emergency Departments.

Indexed as

Platelet TransfusionThrombocytopeniaAdolescentAdultAgedAged, 80 and overBlood BanksBlood Component TransfusionBlood TransfusionChildChild, PreschoolFemaleHumansInfantInfant, NewbornMale

Identifiers

PMID34369873
PMCPMC8486606
OpenAlexW3190359458

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.