Evidence map›Paper›PMID 34369839›Full record

ArticleSubstance use & misuse2021

Lack of Premeditation Predicts Aberrant Behaviors Related to Prescription Opioids in Patients with Chronic Pain: A Cross-Sectional Study.

Gabrielle Hettie, Chinwe Nwaneshiudu, Maisa S Ziadni, Beth D Darnall, Sean C Mackey, Dokyoung S You

Abstract read
In one paragraph

Article in Substance use & misuse, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Gabrielle HettieDepartment Anesthesiology, Perioperative and Pain medicine, Stanford University School of Medicine, Palo Alto, CA, USA.
Chinwe NwaneshiuduDepartment Anesthesiology, Perioperative and Pain medicine, Stanford University School of Medicine, Palo Alto, CA, USA.
Maisa S ZiadniDepartment Anesthesiology, Perioperative and Pain medicine, Stanford University School of Medicine, Palo Alto, CA, USA.ORCID 0000-0001-8371-0646
Beth D DarnallDepartment Anesthesiology, Perioperative and Pain medicine, Stanford University School of Medicine, Palo Alto, CA, USA.ORCID 0000-0003-3590-511X
Sean C MackeyDepartment Anesthesiology, Perioperative and Pain medicine, Stanford University School of Medicine, Palo Alto, CA, USA.ORCID 0000-0001-7744-5348
Dokyoung S YouDepartment Anesthesiology, Perioperative and Pain medicine, Stanford University School of Medicine, Palo Alto, CA, USA.ORCID 0000-0003-0724-7324

Funding

Interdisciplinary Research Training in Pain and Substance Use DisordersT32DA035165 · NIDA · STANFORD UNIVERSITY · PI SEAN C MACKEY · 2013 to 2026
$7.2M
Single Session Pain Catastrophizing Class: Efficacy & Mechanisms for Reducing Opioid Use Among Chronic Pain PatientsK23DA047473 · NIDA · STANFORD UNIVERSITY · PI ZIADNI, MAISA · 2019 to 2023
$796k
Effect of pain catastrophizing on prescription opioid cravingK23DA048972 · NIDA · STANFORD UNIVERSITY · PI YOU, DOKYOUNG SOPHIA · 2019 to 2023
$758k
NIDA NIH HHS K23 DA047473NIDA NIH HHS K23 DA048972NIDA NIH HHS T32 DA035165
6 · The paper itself

Abstract

objectiveIn light of the opioid epidemic, there is a need to identify factors that predict aberrant opioid behaviors including misuse and abuse. Impulsivity has been extensively studied in addiction literature, but not in the context of opioid misuse. Hence, this study aimed to identify which of the impulsivity facets (negative urgency, positive urgency, sensation seeking, lack of perseverance, and lack of premeditation) would predict current aberrant opioid-related behaviors in patients with chronic pain.

methodsData were collected through an online survey from patients with chronic pain who visited a tertiary pain clinic. Patients were predominately female (74%), middle aged (

resultsContrary to expectations, only lack of premeditation predicted higher odds of aberrant opioid-related behaviors in the past 30 days, after controlling for known covariates, and explained 26% of variance. Interestingly, lack of premeditation together with pain catastrophizing as a covariate explained 56% of the variance in aberrant opioid-related behaviors. DISCUSSION: The current study is the first to identify a potential role of lack of premeditation as an impulsivity facet predicting aberrant opioid-related behaviors among patients with chronic pain.

Indexed as

Chronic PainOpioid-Related DisordersAnalgesics, OpioidCross-Sectional StudiesFemaleHumansImpulsive BehaviorMiddle AgedPrescriptionsAnalgesics, Opioidaberrant opioid-related behaviorschronic paincurrent prescription opioid misuseImpulsivitylack of premeditationnon-planning impulsivity

Identifiers

PMID34369839
PMCPMC8928584

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.