Evidence map›Paper›PMID 34369557›Full record

ReviewBioscience reports2021

Intestinal congestion and reperfusion injury: damage caused to the intestinal tract and distal organs.

Yajing Chen, Weigao Pu, Ewetse Paul Maswikiti, Pengxian Tao, Xuemei Li, Dengfeng Wang, Baohong Gu, Yang Yu, Lei Gao, Chengji Zhao and 1 more

Abstract readReview
In one paragraph

Review in Bioscience reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yajing Chen *Department of Tumor Surgery, Lanzhou University Second Hospital, Lanzhou, China.
Weigao Pu *Department of Tumor Surgery, Lanzhou University Second Hospital, Lanzhou, China.ORCID 0000-0001-7824-0176
Ewetse Paul MaswikitiDepartment of Tumor Surgery, Lanzhou University Second Hospital, Lanzhou, China.
Pengxian TaoDepartment of Tumor Surgery, Lanzhou University Second Hospital, Lanzhou, China.
Xuemei LiDepartment of Tumor Surgery, Lanzhou University Second Hospital, Lanzhou, China.
Dengfeng WangDepartment of Tumor Surgery, Lanzhou University Second Hospital, Lanzhou, China.
Baohong GuDepartment of Tumor Surgery, Lanzhou University Second Hospital, Lanzhou, China.
Yang YuDepartment of Tumor Surgery, Lanzhou University Second Hospital, Lanzhou, China.
Lei GaoDepartment of Tumor Surgery, Lanzhou University Second Hospital, Lanzhou, China.
Chengji ZhaoDepartment of Pediatric Surgery, Lanzhou University Second Hospital, Lanzhou, China.
Hao ChenDepartment of Tumor Surgery, Lanzhou University Second Hospital, Lanzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In clinical practice, intestinal autologous diseases, ailments and organ transplants can cause severe congestive damage to the intestinal tract. However, after the etiological factor is gotten rid of and blood flow is free without any hinderance, further damage to the intestinal wall often occurs, causing other related organ dysfunctions. This ultimately results in intestinal congestion reperfusion injury (ICRI). When the structure and function of the intestine are destroyed, bacteria, metabolites and endotoxins in the intestinal tract perfuse and enter the portal vein through the already compromised intestinal mucosa, to the other organs via the liver. Nevertheless, this gives rise to further aggravation of the injury, and reperfusion injury syndrome occurs. ICRI is a very common complication encountered by clinicians, and its harm is more severe and serious as compared with that caused by ischemia-reperfusion. Quite a few number of studies on ICRI have been reported to date. The exact mechanism of the injury is still idiopathic, and effective treatment strategies are still limited. Based on recent studies, this article is aimed at reviewing the destruction, damage mechanisms resulting from ICRI to the intestinal anatomical sites and distant organs. It is geared towards providing new ideas for the prevention and therapeutic approaches of ICRI.

Indexed as

Splanchnic CirculationAnimalsApoptosisBacteriaBacterial TranslocationGastrointestinal MicrobiomeHumansInflammation MediatorsIntestinal DiseasesIntestinesPrognosisReperfusion InjurySignal TransductionInflammation Mediatorsbacterial translocationCongestion-reperfusion injuryinflammatory factorsintestinal barriermicrocirculation

Identifiers

PMID34369557
PMCPMC8421592

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.