Evidence map›Paper›PMID 34369328›Full record

ArticleEpidemiology and infection2021

The performance of Cobas HPV test for cervical cancer screening in Chinese female migrant workers.

Yaojuan He, Wenting Chen, Zhiliang Guo, Danni Yi, Chunfang Cai, Ying Shi, Yanfen Long, Kun Shi

Open access · goldAbstract readComparative StudyEvaluation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Epidemiology and infection, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Yaojuan HeGynecologic Outpatient Department, Guangzhou Women and Children's Medical Center, Guangzhou510621, P.R. China.
Wenting ChenGynecologic Outpatient Department, Guangzhou Women and Children's Medical Center, Guangzhou510621, P.R. China.
Zhiliang GuoGynecologic Outpatient Department, Guangzhou Women and Children's Medical Center, Guangzhou510621, P.R. China.
Danni YiGynecologic Outpatient Department, Guangzhou Women and Children's Medical Center, Guangzhou510621, P.R. China.
Chunfang CaiGynecologic Outpatient Department, Guangzhou Women and Children's Medical Center, Guangzhou510621, P.R. China.
Ying ShiGynecologic Outpatient Department, Guangzhou Women and Children's Medical Center, Guangzhou510621, P.R. China.
Yanfen LongGynecologic Outpatient Department, Guangzhou Women and Children's Medical Center, Guangzhou510621, P.R. China.
Kun ShiGynecologic Outpatient Department, Guangzhou Women and Children's Medical Center, Guangzhou510621, P.R. China.ORCID 0000-0002-2238-7969
Guangzhou Women and Children Medical Center · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to evaluate the performance of Cobas human papillomavirus (HPV) test in cervical cancer screening. A total of 3442 women aged ⩾20 years used Cobas HPV and hybrid capture 2 (HC2) tests were included in this study. Women with any positive result were examined by liquid-based cytology (LBC) test. Then subjects with abnormal LBC or positive Cobas HPV16/18 were further checked by colposcopy to observe the visible lesions to perform the pathological examination. Of these 3442 women, 328 cases were Cobas HPV positive, and the positive rate was 9.53% (95% confidence interval (CI) 8.50-10.53). The positive rate of HPV16, HPV18, and other 12 types of high-risk HPV were 1.54% (95% CI 1.12-1.95), 0.55% (95% CI 0.30-0.80), and 7.44% (95% CI 6.56-8.32), respectively. The coincidence rate of Cobas HPV test and HC2 test was 90% (95% CI 89.00-91.00; Kappa = 0.526) in the primary screening. Age had a non-linear relationship with Cobas HPV positive rate (χ2 = 4.240, P = 0.040) and HPV16/18 typing positive rate (χ2 = 6.610, P = 0.010). Compared with the LBC test, the Cobas HPV test had higher sensitivity when detecting patients with high cervical intraepithelial neoplasia (CIN2+ and CIN3+).

Indexed as

Early Detection of CancerAdultChinaFemaleHumansMiddle AgedPapillomaviridaePapillomavirus InfectionsTransients and MigrantsUterine Cervical NeoplasmsCervical cancerCobas HPV testhuman papillomavirus

Identifiers

PMID34369328
PMCPMC8414596
OpenAlexW3193242725

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.