Evidence map›Paper›PMID 34369293›Full record

ArticleVirulence2021

Orientin mediates protection against MRSA-induced pneumonia by inhibiting Sortase A.

Li Wang, Shisong Jing, Han Qu, Kai Wang, Yajing Jin, Ying Ding, Lin Yang, Hangqian Yu, Yan Shi, Qianxue Li and 1 more

Open access · goldAbstract read
In one paragraph

Article in Virulence, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Antibacterial and Synergistic Effects ofAntibiotics (Basel, Switzerland) · 2025
    Article
  3. Article
  4. Isoliquiritigenin AttenuatesFrontiers in cellular and infection microbiology · 2025
    Article
  5. Article
  6. Article
  7. Inhibitory Effects onPlants (Basel, Switzerland) · 2024
    Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Covalent sortase A inhibitor ML346 preventsRSC medicinal chemistry · 2022
    Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Li WangCollege of Animal Science, Jilin University, Changchun China.
Shisong JingCollege of Animal Science, Jilin University, Changchun China.
Han QuKey Laboratory of Jilin Province for Zoonosis Prevention and Control, Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Changchun, China.
Kai WangKey Laboratory of Jilin Province for Zoonosis Prevention and Control, Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Changchun, China.
Yajing JinCollege of Animal Science, Jilin University, Changchun China.
Ying DingCollege of Animal Science, Jilin University, Changchun China.
Lin YangCollege of Animal Science, Jilin University, Changchun China.
Hangqian YuCollege of Animal Science, Jilin University, Changchun China.
Yan ShiSchool of Pharmaceutical Science, Jilin University, Changchun China.
Qianxue LiKey Laboratory of Jilin Province for Zoonosis Prevention and Control, Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Changchun, China.
Dacheng WangCollege of Animal Science, Jilin University, Changchun China.
Jilin University · CNChinese Academy of Agricultural Sciences · CN

Funding

Validation of methods for detection of Campylobacter in veterinary patientsU18FD005013 · FDA · TEXAS A&M AGRILIFE RESEARCH · PI LAWHON, SARA D., SUCHODOLSKI, JAN · 2013 to 2015
$278k
FDA HHS U18 FD005013
6 · The paper itself

Abstract

Drug-resistant pathogenic

Indexed as

Pneumonia, BacterialStaphylococcal InfectionsAminoacyltransferasesAnimalsBacterial ProteinsCysteine EndopeptidasesFlavonoidsGlucosidesMethicillin-Resistant Staphylococcus aureusMiceAminoacyltransferasesBacterial ProteinsCysteine EndopeptidasesFlavonoidsGlucosidesorientinsortase Aanti-virulenceinhibitororientinpneumoniaSortase AStaphylococcus aureus

Identifiers

PMID34369293
PMCPMC8354611
OpenAlexW3190526909

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.