Evidence map›Paper›PMID 34369285›Full record

ReviewPlatelets2022

Human Platelets and Influenza Virus: Internalization and Platelet Activation.

Josiah Bote, Heather A Corkrey, Milka Koupenova

Abstract readReview
In one paragraph

Review in Platelets, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Platelet and extracellular vesicles in COVID-19 infection and its vaccines.Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis · 2022
    Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Josiah BoteDepartment of Medicine, Division of Cardiovascular Medicine, University of Massachusetts Medical School, Worcester, MA USA.
Heather A CorkreyDepartment of Medicine, Division of Cardiovascular Medicine, University of Massachusetts Medical School, Worcester, MA USA.
Milka KoupenovaDepartment of Medicine, Division of Cardiovascular Medicine, University of Massachusetts Medical School, Worcester, MA USA.

Funding

Mechanisms of platelet reprogramming during influenza infectionR01HL153235 · NHLBI · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI KOUPENOVA, MILKA · 2020 to 2024
$2.1M
NHLBI NIH HHS R01 HL153235
6 · The paper itself

Abstract

Influenza infection has long been associated with prothrombotic outcomes in patients and platelets are the blood component predominantly responsible for thrombosis. In this review, we outline what is known about influenza interaction with human platelets, virion internalization, and viral RNA sensing, and the consequent impact on platelet function. We further discuss activation of platelets by IgG-influenza complexes and touch upon mechanisms of environmental platelet activation that relate to prothrombotic outcomes in patients during infection.

Indexed as

Blood PlateletsHumansInfluenza, HumanPlatelet ActivationImmunityinfectioninfluenzaplateletsthrombosis

Identifiers

PMID34369285
PMCPMC8821732

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.