Evidence map›Paper›PMID 34369272›Full record

ArticleRenal failure2021

Value of quantitative ultrasound and bioelectrical impedance analysis in detecting low bone mineral density in hemodialysis.

Ting Xiang, Li Zhou, Ping Fu, Xue-Ping Yan, Xiao-Qing Zeng

Open access · goldAbstract read
In one paragraph

Article in Renal failure, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Ting XiangDivision of Nephrology, Kidney Research Institute, West China Hospital of Sichuan University, Chengdu, Sichuan, China.
Li ZhouDivision of Nephrology, Kidney Research Institute, West China Hospital of Sichuan University, Chengdu, Sichuan, China.
Ping FuDivision of Nephrology, Kidney Research Institute, West China Hospital of Sichuan University, Chengdu, Sichuan, China.
Xue-Ping YanDivision of Nephrology, Kidney Research Institute, West China Hospital of Sichuan University, Chengdu, Sichuan, China.
Xiao-Qing ZengNutrition Department, West China Hospital of Sichuan University, Chengdu, Sichuan, China.
West China Hospital of Sichuan University · CNSichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPatients on maintenance hemodialysis (MHD) are highly predisposed to low bone mineral density (BMD). This study aims to assess the value of quantitative ultrasound (QUS), bioelectrical impedance analysis (BIA), and their combination in detecting high-risk patients for low BMD in MHD.

methodsPatients' BMD of the total hip, femoral neck, and lumbar spine were measured using dual-energy X-ray absorptiometry (DXA). Bone mineral content (BMC) was assessed using BIA. Calcaneal BMD was measured using QUS. Patients with a T-score of ≤-2.5 were recorded as 'low BMD.'

resultsOverall, 93 subjects (62.37% female; mean age, 60.8 ± 16.2 years) were included in this cross-sectional study; approximately 36.56% met the 'low BMD' criteria. QUS-T score predicted low BMD with an area under the curve (AUC) value of 0.738, sensitivity of 70.59%, and specificity of 76.27%. The AUC for low BMD diagnosis using the BMC index (BMCI) measured through BIA was 0.679 (sensitivity, 91.18%; specificity, 38.98%). On the other hand, the combination of QUS-T score and BMCI yielded a higher AUC value of 0.762 with an improved specificity of 88.14%. Compared with the QUS and BIA alone, the net reclassification improvement (NRI) of the combination model increased by 47.16% (

conclusionThe combination of QUS and BIA is effective in screening for low BMD among MHD patients.

Indexed as

Electric ImpedanceRenal DialysisAbsorptiometry, PhotonAdultAgedArea Under CurveBone DensityBone Diseases, MetabolicCross-Sectional StudiesFemaleFemur NeckHipHumansKidney Failure, ChronicLumbar VertebraeMalebioelectrical impedance analysishemodialysisLow bone mineral densityosteoporosisquantitative ultrasound

Identifiers

PMID34369272
PMCPMC8354166
OpenAlexW3189028088

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.