Evidence map›Paper›PMID 34369264›Full record

ArticleBioengineered2021

Identification of prognostic markers by weighted gene co-expression network analysis in non-small cell lung cancer.

Binglin Chen, Xiaowei Xie, Feifeng Lan, Wenqi Liu

Open access · goldAbstract read
In one paragraph

Article in Bioengineered, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Integration analysis ofBiochemistry and biophysics reports · 2024
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  11. Frontiers in oncology · 2022
    Article
  12. Analysis and verification ofBioengineered · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Binglin ChenDepartment of Radiation Oncology, The Second Affiliated Hospital of Guangxi Medical University, Nanning, China.
Xiaowei XieDepartment of Radiation Oncology, The Second Affiliated Hospital of Guangxi Medical University, Nanning, China.
Feifeng LanDepartment of Radiation Oncology, The Second Affiliated Hospital of Guangxi Medical University, Nanning, China.
Wenqi LiuDepartment of Radiation Oncology, The Second Affiliated Hospital of Guangxi Medical University, Nanning, China.ORCID 0000-0003-4986-1234
Guangxi Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-small cell lung cancer (NSCLC) is one of the fatal tumors and is associated with a poor prognosis. Cell-type identification by estimating relative subsets of RNA transcripts (CIBERSORT) was used to quantify the proportions of 22 types of immune cells. Weighted gene co-expression network analysis (WGCNA) was established from the GSE37745 data, and key modules correlating most with CD8

Indexed as

Carcinoma, Non-Small-Cell LungLung NeoplasmsA549 CellsBiomarkers, TumorComputational BiologyGene Expression ProfilingHumansPrognosisProtein Interaction MapsTranscriptomeBiomarkers, TumorCIBERSORTNon-small cell lung cancerWeighted gene co-expression network analysis

Identifiers

PMID34369264
PMCPMC8806742
OpenAlexW3187476559

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.