Evidence map›Paper›PMID 34369261›Full record

ArticleEpigenetics2022

The effect of experimental lead pollution on DNA methylation in a wild bird population.

Hannu Mäkinen, Kees van Oers, Tapio Eeva, Suvi Ruuskanen

Open access · bronzeAbstract read
In one paragraph

Article in Epigenetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Hannu MäkinenDepartment of Biology, University of Turku, Finland.ORCID 0000-0002-6440-515X
Kees van OersDepartment of Animal Ecology, Netherlands Institute of Ecology (NIOO-KNAW), Wageningen The Netherlands.
Tapio EevaDepartment of Biology, University of Turku, Finland.
Suvi RuuskanenDepartment of Biology, University of Turku, Finland.
University of Turku · FINetherlands Institute of Ecology · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anthropogenic pollution is known to negatively influence an organism's physiology, behaviour, and fitness. Epigenetic regulation, such as DNA methylation, has been hypothesized as a potential mechanism to mediate such effects, yet studies in wild species are lacking. We first investigated the effects of early-life exposure to the heavy metal lead (Pb) on DNA methylation levels in a wild population of great tits (

Indexed as

Environmental PollutantsMetals, HeavyPasseriformesAnimalsDNA MethylationEpigenesis, GeneticLeadEnvironmental PollutantsLeadMetals, Heavyecological epigeneticsecotoxicologyenvironmental epigeneticsparus majorPbpollution

Identifiers

PMID34369261
PMCPMC9235896
OpenAlexW3193180811

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.