Evidence map›Paper›PMID 34369259›Full record

ArticleBioengineered2021

Long non-coding RNA AK006774 inhibits cardiac ischemia-reperfusion injury via sponging miR-448.

Shen Nie, Xiaoya Cui, Jinping Guo, Xiaohua Ma, Haijun Zhi, Shilei Li, Yong Li

Open access · goldAbstract read
In one paragraph

Article in Bioengineered, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Long noncoding RNAOpen medicine (Warsaw, Poland) · 2023
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Shen NieDepartment of Emergency, Cangzhou Central Hospital, Cangzhou, China.
Xiaoya CuiDepartment of Emergency, Cangzhou Central Hospital, Cangzhou, China.
Jinping GuoDepartment of Emergency, Cangzhou Central Hospital, Cangzhou, China.
Xiaohua MaDepartment of Emergency, Cangzhou Central Hospital, Cangzhou, China.
Haijun ZhiDepartment of Emergency, Cangzhou Central Hospital, Cangzhou, China.
Shilei LiDepartment of Emergency, Cangzhou Central Hospital, Cangzhou, China.
Yong LiDepartment of Emergency, Cangzhou Central Hospital, Cangzhou, China.ORCID 0000-0003-4310-040X
Cangzhou Central Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, the incidence and mortality of myocardial infarction (MI) have been increasing throughout the world, threatening public health. Non-coding RNAs (ncRNAs), including microRNAs (miRNAs) and long non-coding RNAs (lncRNAs), play critical roles in the progression of MI. The present study aimed to investigate the role of lncRNA AK006774 in the progression of myocardial infarction and find out novel therapeutic or diagnostic target of myocardial infarction. A mouse ischemia/reperfusion (I/R) model and 2,3,5-Triphenyte-trazoliumchloride (TTC) staining were performed to evaluate the effects of AK006774 on I/R injury

Indexed as

MicroRNAsMyocardial Reperfusion InjuryRNA, Long NoncodingAnimalsApoptosisCells, CulturedDisease Models, AnimalFemaleMiceMice, Inbred C57BLMyocytes, CardiacMicroRNAsMIRN448 microRNA, mouseRNA, Long Noncodingischemia-reperfusion injurylncRNA AK006774miR-448

Identifiers

PMID34369259
PMCPMC8806428
OpenAlexW3190831980

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.