Evidence map›Paper›PMID 34369256›Full record

ArticleBioengineered2021

Discovery of a novel and a rare Kristen rat sarcoma viral oncogene homolog (KRAS) gene mutation in colorectal cancer patients.

Mahmood Rasool, Angel Carracedo, Abdulrahman Sibiany, Faten Al-Sayes, Sajjad Karim, Absarul Haque, Peter Natesan Pushparaj, Muhammad Asif, Niaz M Achakzai

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioengineered, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 4 countries.

Mahmood RasoolCenter of Excellence in Genomic Medicine Research, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.ORCID 0000-0003-2997-5891
Angel CarracedoGenomic Medicine Group, University of Santiago De Compostela, Spain.
Abdulrahman SibianyFaculty of Medicine, KAUH, King Abdulaziz University, Jeddah, Saudi Arabia.
Faten Al-SayesFaculty of Medicine, KAUH, King Abdulaziz University, Jeddah, Saudi Arabia.
Sajjad KarimCenter of Excellence in Genomic Medicine Research, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.ORCID 0000-0003-0907-2097
Absarul HaqueDepartment of Medical Laboratory Technology, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.ORCID 0000-0002-1103-9694
Peter Natesan PushparajCenter of Excellence in Genomic Medicine Research, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.
Muhammad AsifORIC, Department of Biotechnology, Buitems, Quetta, Pakistan.ORCID 0000-0003-4761-837X
Niaz M AchakzaiDepartment of Molecular Biology, City Medical Complex, Kabul, Afghanistan.ORCID 0000-0002-8872-6046
King Abdulaziz University · SABalochistan University of Information Technology, Engineering and Management Sciences · PKKabul Medical University · AFUniversidade de Santiago de Compostela · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal cancer (CRC) is one of the most important causes of morbidity and mortality in the developed world and is gradually more frequent in the developing world including Saudi Arabia. According to the Saudi Cancer Registry report 2015, CRC is the most common cancer in men (14.9%) and the second most prevalent cancer. Oncogenic mutations in the

Indexed as

Proto-Oncogene Proteins p21(ras)AdultAgedAged, 80 and overColorectal NeoplasmsFemaleHumansMaleMiddle AgedModels, MolecularMutationSaudi ArabiaYoung AdultKRAS protein, humanProto-Oncogene Proteins p21(ras)Colorectal cancerDNA sequencingKRASNovel mutationSaudi population

Identifiers

PMID34369256
PMCPMC8806922
OpenAlexW3188631154

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.