Evidence map›Paper›PMID 34369230›Full record

ArticleAIDS care2022

From declining PrEP to PrEP initiation as "first nature" - what changes PrEP initiation decisions among young, Black MSM.

Wenting Huang, Annie Lockard, Colleen F Kelley, David P Serota, Charlotte-Paige M Rolle, Patrick S Sullivan, Eli S Rosenberg, Aaron J Siegler

Abstract read
In one paragraph

Article in AIDS care, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Trial
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  12. Review
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  15. Article
  16. PrEP Acceptance among Eligible Patients Attending the Largest PrEP Clinic in Jackson, Mississippi.Journal of the International Association of Providers of AIDS Care
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Wenting HuangDepartment of Behavioral, Social, and Health Education Sciences, Rollins School of Public Health, Emory University, Atlanta, GA, USA.ORCID 0000-0003-0032-6986
Annie LockardDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA.
Colleen F KelleyDivision of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA.
David P SerotaDivision of Infectious Diseases, Department of Medicine, University of Miami Miller School of Medicine, Miami, FL, USA.
Charlotte-Paige M RolleOrlando Immunology Center, PH-Director of Research Operations, Orlando, FL, USA.
Patrick S SullivanDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA.
Eli S RosenbergDepartment of Epidemiology and Biostatistics, University of Albany School of Public Health, SUNY, Albany, NY, USA.
Aaron J SieglerDepartment of Behavioral, Social, and Health Education Sciences, Rollins School of Public Health, Emory University, Atlanta, GA, USA.

Funding

Making it last: A randomized, controlled trial of a home care system to promote persistence in PrEP careR01MH114692 · NIMH · EMORY UNIVERSITY · PI MAYER, KENNETH H, SIEGLER, AARON JULIUS · 2017 to 2021
$5.8M
Understanding substance use and incident HIV/STI among young black MSMR01DA038196 · NIDA · EMORY UNIVERSITY · PI ROSENBERG, ELI SAMUEL, SULLIVAN, PATRICK SEAN · 2014 to 2018
$3.2M
Defining the rectal mucosa in MSM at risk of HIV infectionK23AI108335 · NIAID · EMORY UNIVERSITY · PI KELLEY, COLLEEN F · 2013 to 2017
$855k
NIAID NIH HHS K23 AI108335NIDA NIH HHS R01 DA038196NIMH NIH HHS R01 MH114692
6 · The paper itself

Abstract

Young Black men who have sex with men (YBMSM) bear a disproportionate burden of HIV, and HIV pre-exposure prophylaxis (PrEP) uptake has been slow. Decisions regarding PrEP initiation change in different life contexts over time. Our YBMSM cohort study found about 1/3 of those who initially declined PrEP subsequently changed and initiated PrEP care. This study explores the process of their PrEP decision changes. The study interviewed participants who initially voiced strong and clear reservations about PrEP, but subsequently started PrEP 1-14 months later. In "review/renew" follow-up interviews, participants reviewed their past statements from a time they declined PrEP, and renew their understanding regarding perspective and behavioral change. Analyzing the data with a positive deviance framework, we found that shifting the decisional balance in favor of PrEP initiation only required change in some areas. There were not consistent factors that prevented or facilitated PrEP uptake. Instead, YBMSM initiated PrEP while maintaining an array of substantial reservations. PrEP initiation discussions should be viewed by health practitioners as a longitudinal process, and routine PrEP offers should be made over time. To optimally facilitate PrEP use among YBMSM, the diverse benefits of PrEP should be emphasized rather than focusing on allaying all concerns.

Indexed as

Anti-HIV AgentsHIV InfectionsPre-Exposure ProphylaxisSexual and Gender MinoritiesBlack or African AmericanCohort StudiesHomosexuality, MaleHumansMaleAnti-HIV Agentspre-exposure prophylaxisYoung Black men who have sex with men

Identifiers

PMID34369230
PMCPMC8825883

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.