Evidence map›Paper›PMID 34368872›Full record

ArticleMolecular medicine reports2021

Ginsenoside Re exhibits neuroprotective effects by inhibiting neuroinflammation via CAMK/MAPK/NF‑κB signaling in microglia.

Iskander Madhi, Ji-Hee Kim, Ji Eun Shin, Younghee Kim

Open access · hybridAbstract read
In one paragraph

Article in Molecular medicine reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 47 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Ginsenoside Re mitigates AβJournal of ginseng research · 2026
    Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. Recent trends in ginseng research.Journal of natural medicines · 2024
    Review
  13. Brain plasticity and ginseng.Journal of ginseng research · 2024
    Review
  14. Article
  15. Ginsenoside Re Mitigates Photooxidative Stress-Mediated Photoreceptor Degeneration and Retinal Inflammation.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2023
    Article
  16. Review
  17. Ginsenosides fromInternational journal of molecular sciences · 2023
    Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Iskander MadhiDepartment of Molecular Biology, College of Natural Sciences, Pusan National University, Busan 46241, Republic of Korea.
Ji-Hee KimKorea Nanobiotechnology Center, Pusan National University, Busan 46241, Republic of Korea.
Ji Eun ShinDepartment of Molecular Biology, College of Natural Sciences, Pusan National University, Busan 46241, Republic of Korea.
Younghee KimDepartment of Molecular Biology, College of Natural Sciences, Pusan National University, Busan 46241, Republic of Korea.
Pusan National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ginsenoside Re (G‑Re) is a panaxatriol saponin and one of the pharmacologically active natural constituents of ginseng (

Indexed as

AnimalsAnti-Inflammatory AgentsApoptosisCalcium-Calmodulin-Dependent Protein KinasesCalcium-Calmodulin-Dependent Protein Kinase Type 4Cell DeathCytokinesGinsenosidesInflammationLipopolysaccharidesMiceMice, Inbred ICRMicrogliaMitogen-Activated Protein Kinase KinasesNeuroinflammatory DiseasesNeuroprotective AgentsAnti-Inflammatory AgentsCalcium-Calmodulin-Dependent Protein KinasesCalcium-Calmodulin-Dependent Protein Kinase Type 4Camk4 protein, mouseCytokinesginsenoside ReGinsenosidesLipopolysaccharidesMitogen-Activated Protein Kinase KinasesNeuroprotective AgentsNF-kappa BNitric OxidepanaxatriolTumor Necrosis Factor-alphaCa2+/calmodulin‑dependent protein kinaseginsenoside Remicroglianeuroinflammationneurotoxicity

Identifiers

PMID34368872
PMCPMC8365412
OpenAlexW3189667288

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.