Evidence map›Paper›PMID 34368739›Full record

ArticleInfection prevention in practice2021

Hand hygiene: virucidal efficacy of a liquid hand wash product against Ebola virus.

T A Cutts, R W Nims, S S Theriault, E Bruning, J R Rubino, M K Ijaz

Abstract read
In one paragraph

Article in Infection prevention in practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Validation of Marburg Virus Inactivation by AVL Buffer.Methods in molecular biology (Clifton, N.J.) · 2025
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

T A CuttsCanadian Science Centre for Human and Animal Health, and J.C. Wilt Infectious Diseases Research Centre, Public Health Agency of Canada, Winnipeg, MB, Canada.
R W NimsRMC Pharmaceutical Solutions, Inc., Longmont, CO, USA.
S S TheriaultUniversity of Manitoba, Winnipeg, MB, Canada.
E BruningGlobal Research & Development for Lysol and Dettol, Reckitt Benckiser LLC, Montvale, NJ, USA.
J R RubinoGlobal Research & Development for Lysol and Dettol, Reckitt Benckiser LLC, Montvale, NJ, USA.
M K IjazGlobal Research & Development for Lysol and Dettol, Reckitt Benckiser LLC, Montvale, NJ, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHand washing is an important targeted hygiene intervention for limiting the spread of infectious agents, including the Ebola virus, which continues to re-emerge. We have assessed the virucidal efficacy of a commercially available liquid hand wash product (LHW) for inactivating Ebola virus.

methodsThe ASTM E1052-11 Standard was used to evaluate the efficacy of an LHW containing the microbicidal active salicylic acid for inactivating Ebola virus - Makona variant suspended in an organic load. Three concentrations (12.5%, 25%, 50%) of three lots of LHW prepared in 440 ppm hard water were evaluated at room temperature for 20, 30, and 60 s contact time.

resultsA 25% solution of the LHW caused 4.5 log

conclusionThese results suggest the potential utility of an appropriately formulated liquid hand wash agent during Ebola virus disease outbreaks for use within healthcare, community, and home settings. Such an LHW should also be effective against other enveloped viruses, such as the pandemic coronavirus SARS-CoV-2.

Indexed as

Ebola virus inactivationEbola virus (Makona C07 variant)Emerging/re-emerging virusesHand hygieneLiquid hand washPrevention of spread of infectious agents including high-risk viruses

Identifiers

PMID34368739
PMCPMC8336303

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.