Duration of carriage of multidrug resistant Enterobacterales in discharged hospital and general practice patients and factors associated with clearance.

Celine van Weerlee, Eric R van der Vorm, Loes Nolles, Saskia Meeuws-van den Ende, Akke K van der Bij

Abstract read

In one paragraph

Article in Infection prevention in practice, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Long-term beneficial effect of faecal microbiota transplantation on colonisation of multidrug-resistant bacteria and resistome abundance in patients with recurrent Clostridioides difficile infection.Genome medicine · 2024
Article

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Celine van WeerleeDepartment of Medical Microbiology, Reinier de Graaf Groep, PO Box 5011, 2600 GA Delft, the Netherlands.

Eric R van der VormDepartment of Medical Microbiology, Reinier de Graaf Groep, PO Box 5011, 2600 GA Delft, the Netherlands.

Loes NollesDepartment of Medical Microbiology, Reinier de Graaf Groep, PO Box 5011, 2600 GA Delft, the Netherlands.

Saskia Meeuws-van den EndeDepartment of Medical Microbiology, Reinier de Graaf Groep, PO Box 5011, 2600 GA Delft, the Netherlands.

Akke K van der BijDepartment of Medical Microbiology, Reinier de Graaf Groep, PO Box 5011, 2600 GA Delft, the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesDutch guidelines recommend contact precautions in patients with multidrug resistant microorganisms cultured during the previous 12 months. To evaluate this policy, duration of carriage of multidrug resistant

methodsFrom January 2013 until May 2016, rectal or faecal samples accompanied by questionnaires on patient characteristics were obtained at time of study inclusion and 3, 6 and 12 months later, in 72 patients with multidrug resistant

resultsClearance was found in 31 patients (43.1% [95%CI: 32.3-54.6]) of which 23 patients had two or more subsequent negative cultures. Twelve patients were classified as intermittent carriers (16.7% [95%CI: 9.8-26.9]) and 29 patients (40.3% [95% CI: 29.7-51.8]) as persistent carriers. Of the intermittent carriers, the majority (n=9) had two negative cultures during the study period. There was no difference in clearance between discharged hospitalized patients and GP patients. The only factor associated with clearance at 12 months in both univariable and multivariable analyses was not traveling to a foreign country (OR=3.5 [95%CI: 1.0-12.4]).

conclusionActive screening for clearance of multidrug resistant

Indexed as

CarriageEPD, electronic patient recordESBL, extended-spectrum beta-lactamaseGP, general practitionerHRMO, highly resistant microorganismsInfection preventionMultidrug resistant Enterobacterales

Identifiers

PMID34368713

DOI10.1016/j.infpip.2020.100066

PMCPMC8335921

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