Evidence map›Paper›PMID 34368698›Full record

ArticleInfection prevention in practice2020

Antimicrobial stewardship program at a tertiary care academic medical hospital: Clinical, microbiological and economic impact. A 5-year temporary descriptive study.

Alfredo Jover-Sáenz, María Fernanda Ramírez-Hidalgo, Montserrat Vallverdú Vidal, Merce García González, Santiago Manuel Cano Marrón, Alfredo Escartín Arias, Miquel Falguera Sacrest, Dolors Castellana-Perelló, Fernando Barcenilla-Gaite, Translational Research Group on Infectious Diseases of Lleida (Head Group, TRIDLE- IRBLleida)g

Abstract read
In one paragraph

Article in Infection prevention in practice, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
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  5. Article
  6. Review
  7. Learning from pragmatic local research.Infection prevention in practice · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Alfredo Jover-SáenzUnidad Territorial de control de Infección Nosocomial, Hospital Universitari Arnau de Vilanova, Lleida, Spain.
María Fernanda Ramírez-HidalgoUnidad Territorial de control de Infección Nosocomial, Hospital Universitari Arnau de Vilanova, Lleida, Spain.
Montserrat Vallverdú VidalServicio de Medicina Intensiva, Hospital Universitari Arnau de Vilanova, Lleida, Spain.
Merce García GonzálezUnidad de Microbiología, Hospital Universitari Arnau de Vilanova, Lleida, Spain.
Santiago Manuel Cano MarrónServicio de Farmacia, Hospital Universitari Arnau de Vilanova, Lleida, Spain.
Alfredo Escartín AriasServicio de Cirugía General y Aparato Digestivo, Hospital Universitari Arnau de Vilanova, Lleida, Spain.
Miquel Falguera SacrestServicio de Medicina Interna, Hospital Universitari Arnau de Vilanova, Lleida, Spain.
Dolors Castellana-PerellóUnidad Territorial de control de Infección Nosocomial, Hospital Universitari Arnau de Vilanova, Lleida, Spain.
Fernando Barcenilla-GaiteUnidad Territorial de control de Infección Nosocomial, Hospital Universitari Arnau de Vilanova, Lleida, Spain.
Translational Research Group on Infectious Diseases of Lleida (Head Group, TRIDLE- IRBLleida)g

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionFew prospective studies analyze, with sufficient duration, the impact of an antimicrobial stewardship program (AMSP) carried out entirely in a hospital.

methodsDescriptive study evaluating the consumption of antimicrobials expressed in defined daily doses (DDD) per 100 hospital occupied bed-days (OBDs) stratified in medical, surgical and intensive care unit (ICU) and the incidence of densities (ID) per 1,000 hospital OBDs of the prevalent multidrug-resistant organisms (MDRO) in a tertiary hospital, over a period of 5 years before and after the implementation of an AMSP. Analysis of direct costs and those associated with hospital stay and mortality.

resultsA total of 32,802 patients with antibiotic treatment were included in the intervention period (2013-2017). Non-imposed advice was exercised in 14.9%. The degree of adherence to recommendation was 87.9%, direct treatment and de-escalation being the most frequently admitted interventions (

conclusionLong-term maintenance of a hospital AMSP was associated with a reduction in antibiotic consumption, especially in ICU, as well as a beneficial ecological impact and economic savings.

Indexed as

Antibiotics costAntimicrobial stewardshipMultidrug-resistant organismsUse antimicrobials

Identifiers

PMID34368698
PMCPMC8335906

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.