ReviewInfection prevention in practice2020
The 2018/19 Ebola epidemic the Democratic Republic of the Congo (DRC): epidemiology, outbreak control, and conflict.
Review in Infection prevention in practice, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 18 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Building evidences in Public Health Emergency Preparedness ("BePHEP" Project)-a systematic review.International journal for equity in health · 2025Pooled it
- Safety and immunogenicity of the two-dose heterologous Ad26.ZEBOV and MVA-BN-Filo Ebola vaccine regimen in children in Sierra Leone: a randomised, double-blind, controlled trial.The Lancet. Infectious diseases · 2022Trial
- A generalized multi-population model for Ebola virus transmission incorporating environmental reservoir dynamics.Infectious medicine · 2026Article
- Limited Durability of Improvements in Infection Prevention and Control Practices Following Reactive Interventions Leaves Healthcare Facilities Vulnerable to Ebola Virus Transmission.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026Article
- Public health emergency response through field epidemiology training and rapid response teams - a scoping review.BMC public health · 2026Article
- Access to licenced vaccines for high-threat infectious diseases: a scoping review and interpretive analysis of Ebola virus disease.BMC infectious diseases · 2026Article
- Donor dependency and pandemic readiness: insights from the 2026 Ebola Bundibugyo outbreak in the East African community.Frontiers in public health · 2026Article
- Progressive Development of a New Tool for Rapid Thematic Analysis of Community Perceptions and Concerns During Health Emergencies.Global health, science and practice · 2025Article
- Evaluation of contact tracing performance during an Ebola virus disease outbreak in a complex security environment: the case of North Kivu province, Democratic Republic of the Congo, 2018-2020.Conflict and health · 2025Article
- Multiple cell types support productive infection and dynamic translocation of infectious Ebola virus to the surface of human skin.Science advances · 2025Article
- Use of a pathogen X tabletop exercise to assess the operational response preparedness of an emerging infectious diseases research network.Frontiers in public health · 2025Article
- Ebola virus disease in children: epidemiology, pathogenesis, management, and prevention.Pediatric research · 2024Review
- Perspectives on Advancing Countermeasures for Filovirus Disease: Report From a Multisector Meeting.The Journal of infectious diseases · 2023Article
- Epidemiology of Ebolaviruses from an Etiological Perspective.Pathogens (Basel, Switzerland) · 2023Review
- Predicting the combined effects of case isolation, safe funeral practices, and contact tracing during Ebola virus disease outbreaks.PloS one · 2023Article
- Ebola virus disease outbreak in the Democratic Republic of the Congo: A mini-review.Annals of medicine and surgery (2012) · 2022Review
- Effect of Recombinant Vesicular Stomatitis Virus-Zaire Ebola Virus Vaccination on Ebola Virus Disease Illness and Death, Democratic Republic of the Congo.Emerging infectious diseases · 2022Article
- Responding to the 2018-2020 Ebola Virus Outbreak in the Democratic Republic of the Congo: Rethinking Humanitarian Approaches.Risk management and healthcare policy · 2021Review
Corrections and comments
- Erratum issued
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Democratic Republic of Congo (DRC) (formerly Zaire) was the location of the first Ebola outbreak, in 1976, and since then there have been a total of ten outbreaks in different parts of the country. The current outbreak, the first in eastern DRC (North Kivu and Ituri provinces), began in July 2018, and by December 2019, there had been 3262 cases and 2232 deaths. Within weeks of the first reported cases, the World Health Organisation (WHO) and the DRC Ministry of Health (MOH) initiated a major response programme, with laboratory support, international agencies providing personnel, and material resources. Unlike previous Ebola outbreaks, including the west Africa epidemic, a proven vaccine, and trial therapeutic agents have been available as part of the outbreak response. Two therapeutic agents, mAb114 and REGN-EB3, both monoclonal antibody derived, have shown case fatality rates (CFR) of around 30%, compared to the overall of 66%. Despite these positive interventions, the outbreak has continued for eighteen months. Underlying the outbreak response has been a high number of violent incidents by local militias, and community mistrust and lack of involvement that has hampered many aspects of the response programme. As a result, many cases are not reported early and not transferred to treatment centres, deaths and increased transmission occur in the community, and the response programme is reaching only a proportion of the cases. New strategies to improve community participation, and integrate the Ebola response into the existing health structure are planned to improve the programme effectiveness.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.