Evidence map›Paper›PMID 34368604›Full record

ReviewAPL bioengineering2021

New contrast agents for photoacoustic imaging and theranostics: Recent 5-year overview on phthalocyanine/naphthalocyanine-based nanoparticles.

Eun-Yeong Park, Donghyeon Oh, Sinyoung Park, Wangyu Kim, Chulhong Kim

Erratum issuedAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in APL bioengineering, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

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  4. A Hybrid Diffusion Model Enhances Multiparametric 3D Photoacoustic Computed Tomography.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Eun-Yeong ParkORCID https://orcid.org/0000-0002-8643-3274
Donghyeon OhDepartments of Electrical Engineering, Convergence IT Engineering, Mechanical Engineering, and Medical Device Innovation Center, Pohang University of Science and Technology (POSTECH), Pohang, Gyeongbuk 37673, South Korea.ORCID https://orcid.org/0000-0002-5553-5649
Sinyoung ParkDepartments of Electrical Engineering, Convergence IT Engineering, Mechanical Engineering, and Medical Device Innovation Center, Pohang University of Science and Technology (POSTECH), Pohang, Gyeongbuk 37673, South Korea.
Wangyu KimDepartments of Electrical Engineering, Convergence IT Engineering, Mechanical Engineering, and Medical Device Innovation Center, Pohang University of Science and Technology (POSTECH), Pohang, Gyeongbuk 37673, South Korea.
Chulhong KimDepartments of Electrical Engineering, Convergence IT Engineering, Mechanical Engineering, and Medical Device Innovation Center, Pohang University of Science and Technology (POSTECH), Pohang, Gyeongbuk 37673, South Korea.ORCID https://orcid.org/0000-0001-7249-1257

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The phthalocyanine (Pc) and naphthalocyanine (Nc) nanoagents have drawn much attention as contrast agents for photoacoustic (PA) imaging due to their large extinction coefficients and long absorption wavelengths in the near-infrared region. Many investigations have been conducted to enhance Pc/Ncs' photophysical properties and address their poor solubility in an aqueous solution. Many diverse strategies have been adopted, including centric metal chelation, structure modification, and peripheral substitution. This review highlights recent advances on Pc/Nc-based PA agents and their extended use for multiplexed biomedical imaging, multimodal diagnostic imaging, and image-guided phototherapy.

Identifiers

PMID34368604
PMCPMC8325568

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.