Evidence map›Paper›PMID 34368506›Full record

ArticleJACC. Basic to translational science2021

Myocardial Infarction and the Fine Balance of Iron.

Rohan Dharmakumar, Anand R Nair, Andreas Kumar, Joseph Francis

Registry-linked trialAbstract readEditorial
In one paragraph

Article in JACC. Basic to translational science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05604131 (Cardiac MRI-guided Deferiprone Therapy for Acute Myocardial Infarction Patients), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05604131 phase2recruitingnot on this mapstarted 2022, after this paper: background citation

Cardiac MRI-guided Deferiprone Therapy for Acute Myocardial Infarction Patients

TypeinterventionalSponsorRohan DharmakumarRan2022 to 2029Enrolled89ConditionsAcute Myocardial Infarction Type 1ArmsDeferiprone Tablets, Placebo
3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Molecular mechanisms and intervention approaches of heart failure (Review).International journal of molecular medicine · 2025
    Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Rohan DharmakumarBiomedical Imaging Research Institute, Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Anand R NairBiomedical Imaging Research Institute, Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Andreas KumarDivision of Cardiology, Department of Medicine, Northern Ontario School of Medicine, Sudbury, Ontario, Canada.
Joseph FrancisDepartment of Comparative Biomedical Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, Louisiana, USA.

Funding

Mechanistic Insights to A Translatable Therapy for Acute Reperfused Hemorrhagic Myocardial InfarctionsR01HL147133 · NHLBI · INDIANA UNIVERSITY INDIANAPOLIS · PI DHARMAKUMAR, ROHAN, FRANCIS, JOSEPH · 2020 to 2023
$3.2M
NHLBI NIH HHS R01 HL147133
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

acute myocardial infarctionheartiron

Identifiers

PMID34368506
PMCPMC8326290

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.