Evidence map›Paper›PMID 34368500›Full record

ArticleAmerican journal of ophthalmology case reports2021

Stromal microsporidial keratitis successfully treated with medical therapy.

Christopher P Donovan, Curtis E Margo, Edgar M Espana

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of ophthalmology case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Christopher P DonovanDepartment of Ophthalmology, University of South Florida, Morsani College of Medicine, 13330 USF Laurel Drive, 4th Floor, Tampa, FL, 33612, USA.
Curtis E MargoDepartment of Ophthalmology, University of South Florida, Morsani College of Medicine, 13330 USF Laurel Drive, 4th Floor, Tampa, FL, 33612, USA.
Edgar M EspanaDepartment of Ophthalmology, University of South Florida, Morsani College of Medicine, 13330 USF Laurel Drive, 4th Floor, Tampa, FL, 33612, USA.
University of South Florida · US

Funding

Regulatory roles for collagen XII in establishment of corneal stromal structure and function and re-establishment after injuryR01EY029395 · NEI · UNIVERSITY OF SOUTH FLORIDA · PI ESPANA, EDGAR MAURICIO · 2018 to 2022
$1.8M
NEI NIH HHS R01 EY029395
6 · The paper itself

Abstract

purposeTo report a case of severe stromal microsporidal keratitis successfully treated with oral albendazole and topical voriconazole. OBSERVATIONS: A 71-year-old man presented with progressive vision loss and corneal opacification for one year. Initial visual acuity was counting fingers attributed to a dense subepithelial opacification. Confocal microscopy and subsequent corneal biopsy lead to the diagnosis of microsporidial keratitis. The patient completed a four-week course of oral albendazole and topical voriconazole which resulted in resolution of the corneal opacification and improvement in visual acuity to 20/250. CONCLUSIONS AND IMPORTANCE: A four-week course of oral albendazole and topical voriconazole was an effective treatment for severe stromal microsporidial keratitis.

Indexed as

Confocal microscopyCorneal biopsyMicrosporidiaStromal keratitis

Identifiers

PMID34368500
PMCPMC8326187
OpenAlexW3183458088

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.