Evidence map›Paper›PMID 34368492›Full record

ArticleCurrent opinion in endocrine and metabolic research2021

Role of obstructive sleep apnea in metabolic risk in PCOS.

Susan Sam, Esra Tasali

Open access · greenAbstract read
In one paragraph

Article in Current opinion in endocrine and metabolic research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Lifestyle medicine pillars for women's heart health.American journal of preventive cardiology · 2025
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Susan SamSection of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Chicago, 5841 S. Maryland Avenue, 60637, Chicago, IL, USA.
Esra TasaliSection of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Chicago, 5841 S. Maryland Avenue, 60637, Chicago, IL, USA.
University of Chicago · US

Funding

YALE CENTER FOR THE: LEARNING &ATTENTIONP41RR013642 · NCRR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI LIN, JACK J · 1998 to 2011
$21.9M
Technology-Supported Treatment of Sleep Apnea in PrediabetesR01DK120312 · NIDDK · UNIVERSITY OF CHICAGO · PI TASALI, ESRA · 2019 to 2023
$3.9M
Mechanisms of Prediabetic States in Obstructive Sleep ApneaR01HL146127 · NHLBI · UNIVERSITY OF CHICAGO · PI TASALI, ESRA · 2019 to 2023
$3.9M
NCRR NIH HHS P41 RR013642NHLBI NIH HHS R01 HL146127NIDDK NIH HHS R01 DK120312
6 · The paper itself

Abstract

Women with polycystic ovary syndrome (PCOS) have a substantially increased risk for diabetes and cardiovascular disease. Obstructive sleep apnea (OSA) is the most common sleep disorder in PCOS. Recent population-based studies indicate a high incidence of OSA among adult women with PCOS. Obesity and increasing age are the main factors for this association. There is strong evidence indicating that OSA is an important modulator of metabolic risk in the general population. There is also some evidence to suggest that OSA may contribute to insulin resistance and glucose intolerance among women PCOS, and thus increase their metabolic risk. The potential mechanisms for adverse metabolic consequences of OSA are likely to be multiple. Whether treatment of OSA in PCOS improves metabolic outcomes requires further rigorous research.

Indexed as

CardiovascularDiabetesGlucoseInsulin resistanceMetabolicObstructive sleep apneaPCOS

Identifiers

PMID34368492
PMCPMC8341449
OpenAlexW3127015768

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.