Evidence map›Paper›PMID 34368362›Full record

ReviewBioMed research international2021

Roles of MicroRNAs in Peripheral Artery In-Stent Restenosis after Endovascular Treatment.

Mo Wang, Weichang Zhang, Lei Zhang, Lunchang Wang, Jiehua Li, Chang Shu, Xin Li

Open access · hybridAbstract readReview
In one paragraph

Review in BioMed research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Phenotypic Switching of VSMCs in the Development of CVDs: Focus on miRs.International journal of molecular sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Mo WangDepartment of Vascular Surgery, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China 410011.
Weichang ZhangDepartment of Vascular Surgery, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China 410011.
Lei ZhangDepartment of Vascular Surgery, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China 410011.
Lunchang WangDepartment of Vascular Surgery, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China 410011.
Jiehua LiDepartment of Vascular Surgery, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China 410011.
Chang ShuDepartment of Vascular Surgery, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China 410011.
Xin LiDepartment of Vascular Surgery, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China 410011.ORCID https://orcid.org/0000-0002-3431-226X
Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endovascular repair including percutaneous transluminal angioplasty (PTA) and stent implantation has become the standard approach for the treatment of peripheral arterial disease; however, restenosis is still the main limited complication for the long-term success of the endovascular repair. Endothelial denudation and regeneration, inflammatory response, and neointimal hyperplasia are major pathological processes occurring during in-stent restenosis (ISR). MicroRNAs exhibit great potential in regulating several vascular biological events in different cell types and have been identified as novel therapeutic targets as well as biomarkers for ISR prevention. This review summarized recent experimental and clinical studies on the role of miRNAs in ISR modification, with the aim of unraveling the underlying mechanism and potential therapeutic strategy of ISR.

Indexed as

Endovascular ProceduresStentsAnimalsArteriesBiomarkersCoronary RestenosisHumansMicroRNAsBiomarkersMicroRNAs

Identifiers

PMID34368362
PMCPMC8337102
OpenAlexW3184281115

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.