Evidence map›Paper›PMID 34368346›Full record

ReviewBioMed research international2021

Autologous Platelet-Rich Plasma Efficacy in the Field of Regenerative Medicine: Product and Quality Control.

Marius Nicolae Popescu, Mădălina Gabriela Iliescu, Cristina Beiu, Liliana Gabriela Popa, Mara Mădălina Mihai, Mihai Berteanu, Anca Mirela Ionescu

Abstract readReview
In one paragraph

Review in BioMed research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

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  12. The Biological Role of Platelet Derivatives in Regenerative Aesthetics.International journal of molecular sciences · 2024
    Review
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  14. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Marius Nicolae PopescuDepartment of Physical and Rehabilitation Medicine-"Elias" Emergency University Hospital, "Carol Davila" University of Medicine and Pharmacy, 8 Eroii Sanitari Blvd, 050474 Bucharest, Romania.
Mădălina Gabriela IliescuFaculty of Medicine, 'Ovidius' University of Constanta, 1 University Alley, Campus-Corp B, 900470 Constanta, Romania.
Cristina BeiuDepartment of Oncologic Dermatology-"Elias" Emergency University Hospital, "Carol Davila" University of Medicine and Pharmacy, 8 Eroii Sanitari Blvd, 050474 Bucharest, Romania.ORCID https://orcid.org/0000-0003-4632-576X
Liliana Gabriela PopaDepartment of Oncologic Dermatology-"Elias" Emergency University Hospital, "Carol Davila" University of Medicine and Pharmacy, 8 Eroii Sanitari Blvd, 050474 Bucharest, Romania.
Mara Mădălina MihaiDepartment of Oncologic Dermatology-"Elias" Emergency University Hospital, "Carol Davila" University of Medicine and Pharmacy, 8 Eroii Sanitari Blvd, 050474 Bucharest, Romania.
Mihai BerteanuDepartment of Physical and Rehabilitation Medicine-"Elias" Emergency University Hospital, "Carol Davila" University of Medicine and Pharmacy, 8 Eroii Sanitari Blvd, 050474 Bucharest, Romania.
Anca Mirela Ionescu"Carol Davila" University of Medicine and Pharmacy, 8 Eroii Sanitari Blvd, 050474 Bucharest, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Platelet-rich plasma (PRP) has emerged as a significant regenerative therapy used alone or combined mainly with stem cells, autologous fat grafts, hyaluronic acid, and biomaterials in a variety of medical fields, especially in hair regrowth, wound healing, and sports and rehabilitation medicine. However, the results obtained with this biologic therapy are heterogeneous and conflicting. The observed disparities in the effectiveness of PRP therapies may be due to a lack of standardization in blood processing and preparation. This article is aimed at reviewing the main biological parameters that need to be documented for a thorough reporting of quantitative and qualitative characteristics of the PRP injected, to allow a comparison between the quality of samples and the clinically obtained results and advance the efforts towards treatment standardization.

Indexed as

Regenerative MedicineHumansPlatelet-Rich PlasmaPractice Patterns, Physicians'Quality ControlSports MedicineWound Healing

Identifiers

PMID34368346
PMCPMC8346315

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.