Evidence map›Paper›PMID 34368339›Full record

ArticleWorld journal of clinical cases2021

Fruquintinib beneficial in elderly patient with neoplastic pericardial effusion from rectal cancer: A case report.

Ying Zhang, Jia-Yun Zou, Yan-Yan Xu, Jing-Ni He

Open access · diamondAbstract readCase Reports
In one paragraph

Article in World journal of clinical cases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Ying ZhangDepartment of Clinical Oncology, Shengjing Hospital of China Medical University, Shenyang 110022, Liaoning Province, China.
Jia-Yun ZouDepartment of Clinical Oncology, Shengjing Hospital of China Medical University, Shenyang 110022, Liaoning Province, China.
Yan-Yan XuDepartment of Clinical Oncology, Shengjing Hospital of China Medical University, Shenyang 110022, Liaoning Province, China.
Jing-Ni HeDepartment of General Surgery, Shengjing Hospital of China Medical University, Shenyang 110022, Liaoning Province, China. hejn@sj-hospital.org.
China Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNeoplastic pericardial effusion (NPE) is a rare consequence of rectal cancer and carries a poor prognosis. Optimal management has yet to be determined. Fruquintinib is an oral anti-vascular endothelial growth factor receptor tyrosine kinase inhibitor approved by the China Food and Drug Administration in September 2018 as third-line treatment of metastatic colorectal cancer. CASE SUMMARY: Herein, we report an elderly patient with NPE from rectal cancer who responded to the use of fruquintinib. In March 2015, a 65-year-old Chinese woman diagnosed with KRAS-mutated adenocarcinoma of the rectum was subjected to proctectomy, adjuvant concurrent chemoradiotherapy, and adjuvant chemotherapy. By October 2018, a mediastinal mass was detected

conclusionFruquintinib may confer good survival benefit in elderly patients with NPEs due to rectal cancer.

Indexed as

Anti-vascular endothelial growth factor receptor tyrosine kinase inhibitorCase reportFruquintinibNeoplastic pericardial effusionRectal cancer

Identifiers

PMID34368339
PMCPMC8316928
OpenAlexW3183765815

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.