Evidence map›Paper›PMID 34368311›Full record

ArticleWorld journal of clinical cases2021

Fatigue prevalence in men treated for prostate cancer: A systematic review and meta-analysis.

Yu-Hong Luo, Yan-Wei Yang, Chang-Fu Wu, Chao Wang, Wen-Juan Li, Hong-Chen Zhang

Abstract read
In one paragraph

Article in World journal of clinical cases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Measurement of patients' acceptable symptom levels and priorities for symptom improvement in advanced prostate cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  6. Article
  7. Influence of androgen deprivation therapy on physical performance and muscle strength in prostate cancer patients - a systematic review.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2025
    Review
  8. Review
  9. Article
  10. Article
  11. Health-related quality of life in long-term Caribbean prostate cancer survivors: comparisons with prostate cancer-free men.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yu-Hong LuoSchool of Nursing, Lanzhou University, Lanzhou 730000, Gansu Province, China.
Yan-Wei YangDepartment of Stomatology, The 940th Hospital of Joint Logistic Support Force of the Chinese People's Liberation Army, Lanzhou 730050, Gansu Province, China.
Chang-Fu WuThe First Clinical Medical College, Lanzhou University, Lanzhou 730000, Gansu Province, China.
Chao WangSchool of Clinical Medicine, Gansu University of Chinese Medicine, Lanzhou 730000, Gansu Province, China.
Wen-Juan LiDepartment of Respiratory and Critical Care, Henan Provincial Hospital, Zhengzhou 450003, Henan Province, China.
Hong-Chen ZhangSchool of Nursing, Lanzhou University, Lanzhou 730000, Gansu Province, China. hczhang@lzu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe side effects of prostate cancer (PCa) treatment are very prominent, with cancer-related fatigue (CRF) being the most common. Fatigue is a distressing symptom that interferes with daily functioning and seriously affects patient quality of life during, and for many years after, treatment. However, compared with other types of cancer, such as breast cancer, little is known about the prevalence of PCa-related fatigue.

aimTo determine the prevalence of CRF in patients with PCa.

methodsA systematic search of EMBASE, PubMed, Web of Science, Cochrane Library, Chinese National Knowledge Infrastructure, WANFANG DATA, Technology Journal Database and the Chinese Biological Medical Database was conducted up to July 28, 2020. Included studies measured the incidence of PCa-related fatigue and differentiated fatigue outcomes (incidence) between treatment modalities and fatigue assessment times. In our meta-analysis, both fixed and random-effects models were used to estimate the pooled prevalence of PCa-related fatigue. Subgroup analyses were performed using treatment modalities and fatigue assessment times. Publication and sensitivity bias analyses were performed to test the robustness of the associations.

resultsFourteen studies, involving 4736 patients, were eligible for the review. The pooled CRF prevalence was 40% in a total sample of 4736 PCa patients [95% confidence interval (CI): 29-52;

conclusionOur meta-analysis showed that fatigue is a common symptom in men with PCa, especially those using hormone therapy.

Indexed as

FatigueMeta-analysisPrevalenceProstate cancerSystematic review

Identifiers

PMID34368311
PMCPMC8316927

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.