ReviewFrontiers in cardiovascular medicine2021
Secondary Tricuspid Regurgitation: Pathophysiology, Incidence and Prognosis.
Review in Frontiers in cardiovascular medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- Association between tricuspid regurgitation and heart failure outcomes: A meta-analysis.ESC heart failure · 2025Pooled it
- Tricuspid Annuloplasty: Is It a Step That Should Not Be Ignored in Mitral Valve Surgery?Interdisciplinary cardiovascular and thoracic surgery · 2026Article
- Surgical repair of functional tricuspid regurgitation by drawing the anterior and posterior papillary muscles towards the septum, corrected regurgitation and restored physiologic valve kinematics.The Journal of thoracic and cardiovascular surgery · 2026Article
- Progression or persistence of tricuspid regurgitation after mitral valve replacement in patients with pre-operative moderate tricuspid regurgitation.Indian journal of thoracic and cardiovascular surgery · 2025Article
- Efficacy and Safety of Transcatheter Tricuspid Valve Replacement in Patients With Moderate to Severe Tricuspid Regurgitation: A Systematic Review and Meta-Analysis on Clinical Outcomes and Echocardiographic Indices.Health science reports · 2025Review
- Robustness of tricuspid regurgitation reduction at 1 year following edge-to-edge repair for primary tricuspid regurgitation.Clinical research in cardiology : official journal of the German Cardiac Society · 2025Article
- Exercise testing in patients with tricuspid regurgitation undergoing transcatheter tricuspid valve intervention.Clinical research in cardiology : official journal of the German Cardiac Society · 2025Article
- Healthcare utilization and expenditures in patients with tricuspid regurgitation: A population-based cohort study.International journal of cardiology. Heart & vasculature · 2024Article
- Tricuspid edge-to-edge repair for tricuspid valve prolapse and flail leaflet: feasibility in comparison to patients with secondary tricuspid regurgitation.European heart journal. Cardiovascular Imaging · 2024Article
- Transcatheter Tricuspid Valve Intervention for the Treatment of Tricuspid Regurgitation with TriClip: All You Need to Know.Heart international · 2024Review
- Clinical outcomes and progression rate of tricuspid regurgitation in patients with rheumatic mitral valve disease.Open heart · 2023Article
- Echocardiography Imaging of the Right Ventricle: Focus on Three-Dimensional Echocardiography.Diagnostics (Basel, Switzerland) · 2023Review
- Transcatheter Tricuspid Valve Replacement: Case Selection, Technical Considerations, and Procedural Planning.US cardiology · 2023Review
- Prevalence and risk prediction value of tricuspid regurgitation by echocardiography in precapillary pulmonary hypertension.BMC pulmonary medicine · 2022Article
- Transcatheter Tricuspid Valve Replacement: A Feasible Solution to a Real-world Problem.Reviews in cardiovascular medicine · 2022Review
- Right coronary artery deformation and injury following tricuspid valve surgery.Frontiers in cardiovascular medicine · 2022Article
- Restructuring the Heart From Failure to Success: Role of Structural Interventions in the Realm of Heart Failure.Frontiers in cardiovascular medicine · 2022Review
- Atrial Mitral and Tricuspid Regurgitation: Sex Matters. A Call for Action to Unravel the Differences Between Women and Men.Frontiers in cardiovascular medicine · 2022Review
- Tricuspid Annulus Dilation in Patients With Combined Functional Tricuspid Regurgitation and Left-Heart Valvular Disease: Does Septal Annulus Not Dilate?Frontiers in cardiovascular medicine · 2022Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tricuspid regurgitation (TR) can be divided into primary and secondary origins. Primary TR is mostly caused by infective endocarditis, leaflet perforation, entrapment after device placement and congenital abnormalities. The natural cause of secondary (functional) TR is not well-understood and underdiagnoses is likely. Because symptoms such as ascites, edema and hepatomegaly usually manifest at a late state, assessment of TR is challenging requiring a multiparametric approach. Secondary TR can be subdivided into four morphologic types according to the underlying mechanism: Left-heart related TR, precapillary pulmonary hypertension related TR, right ventricular disease related TR and isolated TR.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.