Evidence map›Paper›PMID 34368206›Full record

ArticleFrontiers in nutrition2021

Chaya Leaf Decreased Triglycerides and Improved Oxidative Stress in Subjects With Dyslipidemia.

Martha Guevara-Cruz, Isabel Medina-Vera, Trinidad Eugenia Cu-Cañetas, Yusef Cordero-Chan, Nimbe Torres, Armando R Tovar, Claudia Márquez-Mota, José Moisés Talamantes-Gómez, Carlos Pérez-Monter, Roberto Lugo and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Martha Guevara-CruzDepartamento de Fisiología de la Nutrición, Instituto Nacional de Nutrición y Ciencias Médicas Salvador Zubirán, Ciudad de México, Mexico.
Isabel Medina-VeraTecnologico de Monterrey, Escuela de Medicina y Ciencias de la Salud, Monterrey, Mexico.
Trinidad Eugenia Cu-CañetasEscuela de Salud, Universidad Modelo, Mérida, Mexico.
Yusef Cordero-ChanEscuela de Salud, Universidad Modelo, Mérida, Mexico.
Nimbe TorresDepartamento de Fisiología de la Nutrición, Instituto Nacional de Nutrición y Ciencias Médicas Salvador Zubirán, Ciudad de México, Mexico.
Armando R TovarDepartamento de Fisiología de la Nutrición, Instituto Nacional de Nutrición y Ciencias Médicas Salvador Zubirán, Ciudad de México, Mexico.
Claudia Márquez-MotaDepartamento de Nutrición Animal y Bioquímica, Facultad de Medicina Veterinaria y Zootecnia, Universidad Nacional Autónoma de México (FMVZ-UNAM), Ciudad de México, Mexico.
José Moisés Talamantes-GómezDepartamento de Nutrición Animal y Bioquímica, Facultad de Medicina Veterinaria y Zootecnia, Universidad Nacional Autónoma de México (FMVZ-UNAM), Ciudad de México, Mexico.
Carlos Pérez-MonterDepartamento de Gastroenterología, Instituto Nacional de Nutrición y Ciencias Médicas Salvador Zubirán, Ciudad de México, Mexico.
Roberto LugoHospital Regional de Alta Especialidad de la Península de Yucatán, Mérida, Mexico.
Ana Ligia Gutiérrez-SolisHospital Regional de Alta Especialidad de la Península de Yucatán, Mérida, Mexico.
Azalia Avila-NavaHospital Regional de Alta Especialidad de la Península de Yucatán, Mérida, Mexico.
Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán · MXHospital Regional de Alta Especialidad del Bajío · MXUniversidad Modelo · MXUniversidad Nacional Autónoma de México · MXTecnológico de Monterrey · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chaya is an edible leaf popular in Mexico and Central America because of its high nutritional value. Studies in animal models have demonstrated the beneficial effects of Chaya, which include reduction of circulating lipids and increase in antioxidant activity. However, its hypolipidemic and antioxidant effects have not been demonstrated in humans. Thus, the aim of the present study was to evaluate the effect of Chaya on the lipid profile, lipid peroxidation, inflammation, and peripheral blood mononuclear cell gene expression in a population with dyslipidemia. We performed a single-arm trial in 30 participants with dyslipidemia who consumed 500 mL of Chaya beverage per day over a 6-week period. Interestingly, we observed a significant decrease in serum triglyceride concentration (

Indexed as

antioxidant activityChayadyslipidemiaoxidative stresstriglycerides

Identifiers

PMID34368206
PMCPMC8343181
OpenAlexW3184874297

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.