Evidence map›Paper›PMID 34368200›Full record

ArticleFrontiers in medicine2021

Risk Factors for Band Keratopathy in Aphakic Eyes With Silicone Oil Tamponade for Open-Globe Injuries: A Multicenter Case-Control Study.

Kai He, Mengyu Liao, Yun Zhu, Bohao Cui, Haoyu Chen, Ting Wang, Nan Wu, Zhenggao Xie, Jing Luo, Yong Wei and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Carbon footprint of Pars plana vitrectomies in rhegmatogenous retinal detachment in Germany between 2013 and 2023 - A cohort study of fluorinated gas emissions.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025
    Article
  3. Review
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 10 institutions in 1 country.

Kai HeDepartment of Ophthalmology, Tianjin Medical University General Hospital, Tianjin Medical University, Tianjin, China.
Mengyu LiaoDepartment of Ophthalmology, Tianjin Medical University General Hospital, Tianjin Medical University, Tianjin, China.
Yun ZhuDepartment of Epidemiology and Biostatistics, School of Public Health, Tianjin Medical University, Tianjin, China.
Bohao CuiDepartment of Ophthalmology, Tianjin Medical University General Hospital, Tianjin Medical University, Tianjin, China.
Haoyu ChenDepartment of Ophthalmology, Joint Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong, Shantou, China.
Ting WangState Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Department of Ophthalmology, Shandong Eye Institute, Eye Hospital of Shandong First Medical University, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, China.
Nan WuDepartment of Ophthalmology, Southwest Hospital, Southwest Eye Hospital, Army Medical University, Chongqing, China.
Zhenggao XieDepartment of Ophthalmology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China.
Jing LuoDepartment of Ophthalmology, The Second Xiangya Hospital, Central South University, Changsha, China.
Yong WeiThe Eye Hospital of Wenzhou Medical University, Wenzhou, China.
Zhiliang WangDepartment of Ophthalmology, Huashan Hospital of Fudan University, Shanghai, China.
Heding ZhouDepartment of Ophthalmology, Ningbo Eye Hospital, Wenzhou Medical University, Ningbo, China.
Zhansheng ShenDepartment of Ophthalmology, Zhengzhou Second Hospital, Zhengzhou, China.
Hua YanDepartment of Ophthalmology, Tianjin Medical University General Hospital, Tianjin Medical University, Tianjin, China.
Tianjin Medical University General Hospital · CNAffiliated Eye Hospital of Wenzhou Medical College · CNArmy Medical University · CNChinese University of Hong Kong · CNHuashan Hospital · CNNanjing Drum Tower Hospital · CNSecond Affiliated Hospital of Zhengzhou University · CNSecond Xiangya Hospital of Central South University · CNShandong Eye Hospital · CNTianjin Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Band keratopathy (BK) is a common complication in aphakic eyes with silicone oil tamponade for open-globe injury (OGI), characterized by the grayish-white opacities in the cornea, resulting in a significantly decreased vision when extending to the visual axis. To identify the risk factors for BK in aphakic eyes following vitreoretinal surgical treatment with silicone oil tamponade for OGIs, we performed a multicenter case-control study. The incidence of BK was 28% (28/100 eyes). The multivariate binary logistic regression revealed the silicone oil retention time (SORT) ≥6 months and zone III injury were significant risk factors for BK. From the hierarchical interaction, SORT ≥6 months had a significant risk for BK in eyes with rupture, aniridia, and zone III injury, while zone III injury had a significant risk for BK in eyes with rupture, incomplete/complete iris, and SORT ≥6 months. By using restricted cubic splines with three knots at the 25th, 50th, and 75th centiles to model the association of SORT with BK, we also found a marked increase in the risk for BK at ≥10 months and a slow increase after 6 months, but almost stable within 4-6 months.

Indexed as

aphakic eyeband keratopathyopen-globe injuriessilicone oil retention timesilicone oil tamponadezone of injury

Identifiers

PMID34368200
PMCPMC8342885
OpenAlexW3186953281

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.