Evidence map›Paper›PMID 34368197›Full record

ArticleFrontiers in medicine2021

Case Report: Infection With SARS-CoV-2 in the Presence of High Levels of Vaccine-Induced Neutralizing Antibody Responses.

Bianca Schulte, Benjamin Marx, Marek Korencak, Dorian Emmert, Souhaib Aldabbagh, Anna Maria Eis-Hübinger, Hendrik Streeck

Open access · goldAbstract readCase Reports
In one paragraph

Article in Frontiers in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Bianca SchulteInstitute for Virology, University Hospital Bonn, Bonn, Germany.
Benjamin MarxInstitute for Virology, University Hospital Bonn, Bonn, Germany.
Marek KorencakInstitute for Virology, University Hospital Bonn, Bonn, Germany.
Dorian EmmertInstitute for Virology, University Hospital Bonn, Bonn, Germany.
Souhaib AldabbaghInstitute for Virology, University Hospital Bonn, Bonn, Germany.
Anna Maria Eis-HübingerInstitute for Virology, University Hospital Bonn, Bonn, Germany.
Hendrik StreeckInstitute for Virology, University Hospital Bonn, Bonn, Germany.
University Hospital Bonn · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present a case of SARS-CoV-2 B.1. 525 infection in a healthcare worker despite the presence of highly neutralizing, multivariant-specific antibodies 7 weeks after full vaccination with the mRNA vaccine BNT162b2. We show that the virus replicated to high levels in the upper respiratory tract over the course of several days in the presence of strong antibody responses. The virus was readily propagatable

Indexed as

breakthrough infectionmRNA vaccinesneutralizing antibodiesSARS-CoV-2virus variants

Identifiers

PMID34368197
PMCPMC8342944
OpenAlexW3189236029

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.