Evidence map›Paper›PMID 34368122›Full record

ArticleFrontiers in cell and developmental biology2021

Proliferation of Lung Epithelial Cells Is Regulated by the Mechanisms of Autophagy Upon Exposure of Soots.

Rituraj Niranjan, Kaushal Prasad Mishra, Sachchida Nand Tripathi, Ashwani Kumar Thakur

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
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  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Rituraj NiranjanLaboratory 6, Department of Biological Sciences and Bioengineering (BSBE), Indian Institute of Technology, Kanpur, India.
Kaushal Prasad MishraLaboratory 6, Department of Biological Sciences and Bioengineering (BSBE), Indian Institute of Technology, Kanpur, India.
Sachchida Nand TripathiDepartment of Civil Engineering, Centre for Environmental Science and Engineering, Indian Institute of Technology Kanpur, Kanpur, India.
Ashwani Kumar ThakurLaboratory 6, Department of Biological Sciences and Bioengineering (BSBE), Indian Institute of Technology, Kanpur, India.
Indian Institute of Technology Kanpur · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSoots are known to cause many diseases in humans, but their underlying mechanisms of toxicity are still not known. Here, we report that soots induce cell proliferation of lung epithelial cells

resultsFullerene soot and diesel exhaust particles (DEP) induced cell proliferation of lung epithelial, A549 cells

conclusionIt can be said that distinct autophagic mechanisms are operational in cell proliferation of lung epithelial cells due to soots, which may be responsible for different diseases. Understanding the mechanism of these pathways provides some important targets, which can be utilized for the development of future therapeutics.

Indexed as

autophagycell proliferationenvironmental sootsfullerene sootp62/SQSTM1particulate matterpollutants (environmental)reactive oxygen species

Identifiers

PMID34368122
PMCPMC8335634
OpenAlexW3183185670

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.