ReviewFrontiers in bioengineering and biotechnology2021
Current Advances in the Development of Decellularized Plant Extracellular Matrix.
Review in Frontiers in bioengineering and biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Ethical Implications of Tissue Engineering for Regenerative Purposes: A Systematic Review.Tissue engineering. Part B, Reviews · 2023Pooled it
- Growing Relevance of Decellularized Plant Material as Functional Scaffolds in Tissue Engineering and Cultured Meat: A Scoping Review on Recent Advances, Challenges, and Future Directions.Annals of biomedical engineering · 2026Review
- Decellularized matrix grafts and peripheral nerve regeneration.Neural regeneration research · 2026Article
- Plant-Based Scaffolds in Tissue Engineering: Structure-Function, Processing, and Clinical Outlook-A Review.Annals of biomedical engineering · 2026Review
- A perfusable decellularized plant-based air-liquid-interface-on-a-chip for investigating inorganic dust aerosol exposure.Scientific reports · 2025Article
- Cellulose Plant-Derived Scaffolds as a Tool for Myometrium Modeling.International journal of molecular sciences · 2025Article
- Engineering vascular grafts from decellularized plants: Advances and challenges.Histology and histopathology · 2025Review
- Acellular Extracellular Matrix Scaffolds in Regenerative Medicine: Advances in Decellularization and Clinical Applications.Journal of functional biomaterials · 2025Review
- Article
- Mechanical Properties and Microstructure of Decellularized Brown Seaweed Scaffold for Tissue Engineering.Bioengineering (Basel, Switzerland) · 2025Article
- Optimization and Standardization of Plant-Derived Vascular Scaffolds.International journal of molecular sciences · 2025Article
- Decellularized Persian walnut leaf (Frontiers in bioengineering and biotechnology · 2025Article
- The potent osteo-inductive capacity of bioinspired brown seaweed-derived carbohydrate nanofibrous three-dimensional scaffolds.Marine life science & technology · 2024Article
- Plant-Based Decellularization: A Novel Approach for Perfusion-Compatible Tissue Engineering Structures.Journal of microbiology and biotechnology · 2024Review
- Cellulose as a sustainable scaffold material in cultivated meat production.Current research in food science · 2024Article
- Article
- Article
- Small-Caliber Vascular Grafts Engineered from Decellularized Leaves and Cross-Linked Gelatin.Tissue engineering. Part A · 2023Article
- Bioprocessing by Decellularized Scaffold Biomaterials in Cultured Meat: A Review.Bioengineering (Basel, Switzerland) · 2022Review
- Celery-derived scaffolds with liver lobule-mimicking structures for tissue engineering transplantation.Smart medicine · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
An imbalance exists between the supply of organs for transplantation and the number of patients in the donor transplant waiting lists. Current use of autologous, synthetic, and animal-derived grafts for tissue replacement is limited by the low availability, poor biocompatibility, and high cost. Decellularized plant scaffolds with remarkable physical similarities to human organs have recently emerged and have been found to present favorable characteristics that make them suitable as an alternative biomaterial, such as a superficial surface area, excellent water transport and retention, pre-existing vascular networks, interconnected porosity, and a wide range of mechanical properties. In addition to their unique and superior biocompatibility, plant-derived scaffolds present the advantages of low production cost, no ethical or supply constraints, simple operation and suitability for large-scale production and research. However, there are still some problems and deficiencies in this field, such as immature decellularization standards and methods, insufficient research on the biocompatibility of plant extracellular matrix. At present, research on decellularized plant extracellular matrix is still in its infancy, and its applicability to tissue engineering needs to be further improved. In this review, the current research progress on decellularized plant scaffolds is reviewed, the problems to be solved and future research directions are discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.