ArticleFrontiers in oncology2021
Quantitative Prediction of Microsatellite Instability in Colorectal Cancer With Preoperative PET/CT-Based Radiomics.
Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 5 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 5 syntheses or guidelines pooled it, 29 citations in OpenAlex.
- FDG-PET/CT Parameters for distinguishing high and low microsatellite instability in colorectal cancer: A systematic review and Meta-analysis.Annals of nuclear medicine · 2026Pooled it
- Radiomics for predicting microsatellite instability-high status in colorectal cancer: a systematic review and meta-analysis.World journal of surgical oncology · 2026Pooled it
- Diagnostic performance of radiomics models for preoperative prediction of microsatellite instability status in endometrial cancer: a systematic review and meta-analysis.Abdominal radiology (New York) · 2025Pooled it
- Radiomics in precision medicine for colorectal cancer: a bibliometric analysis (2013-2023).Frontiers in oncology · 2024Pooled it
- Systematic review of machine learning-based radiomics approach for predicting microsatellite instability status in colorectal cancer.La Radiologia medica · 2023Pooled it
- Image Analysis as tool for Predicting Colorectal Cancer Molecular Alterations: A Scoping Review.Molecular imaging and radionuclide therapy · 2025Article
- Radiomics in sporadic microsatellite instable, mismatch repair deficient and Lynch syndrome-associated pancreatic ductal adenocarcinoma: a pilot study.Frontiers in oncology · 2025Article
- Non-invasive CT radiomic biomarkers predict microsatellite stability status in colorectal cancer: a multicenter validation study.European radiology experimental · 2024Article
- A radiomics-boosted deep-learning for risk assessment of synchronous peritoneal metastasis in colorectal cancer.Insights into imaging · 2024Article
- Clinical application ofJapanese journal of radiology · 2024Review
- Radiomics in colorectal cancer patients.World journal of gastroenterology · 2023Review
- Prediction of Microsatellite Instability in Colorectal Cancer Using a Machine Learning Model Based on PET/CT Radiomics.Yonsei medical journal · 2023Article
- Radiomics-guided checkpoint inhibitor immunotherapy for precision medicine in cancer: A review for clinicians.Frontiers in immunology · 2023Review
- Predictive value of intratumoral-metabolic heterogeneity derived fromFrontiers in oncology · 2023Article
- Correlations among KRAS Mutation, Microsatellite Instability, and 18F-FDG Uptake in Colon Cancer.Asian Pacific journal of cancer prevention : APJCP · 2022Article
- Radiomics in Oncological PET Imaging: A Systematic Review-Part 2, Infradiaphragmatic Cancers, Blood Malignancies, Melanoma and Musculoskeletal Cancers.Diagnostics (Basel, Switzerland) · 2022Review
- Clinicopathological characteristics of high microsatellite instability/mismatch repair-deficient colorectal cancer: A narrative review.Frontiers in immunology · 2022Review
- CT-based radiomic nomogram for preoperative prediction of DNA mismatch repair deficiency in gastric cancer.Frontiers in oncology · 2022Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesMicrosatellite instability (MSI) status is an important hallmark for prognosis prediction and treatment recommendation of colorectal cancer (CRC). To address issues due to the invasiveness of clinical preoperative evaluation of microsatellite status, we investigated the value of preoperative
methodsA total of 173 patients that underwent
resultsThe ensemble model was constructed based on two radiomic features and achieved an 82.8% AUC for predicting the MSI status of colorectal cancer patients. The sensitivity, specificity, and accuracy were 83.3, 76.3, and 76.8%, respectively. The significant correlation of the selected two radiomic features with multiple effective clinical features was identified (p < 0.05).
conclusion
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.