Evidence map›Paper›PMID 34367678›Full record

ArticleJournal of clinical and translational science2021

Development of a multi-component intervention to promote participation of Black and Latinx individuals in biomedical research.

Maria I Danila, Jeroan J Allison, Karin Valentine Goins, Germán Chiriboga, Melissa Fischer, Melissa Puliafico, Amy S Mudano, Elizabeth J Rahn, Jeanne Merchant, Colleen E Lawrence and 14 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical and translational science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Interventions to Improve COVID-19 Vaccine Hesitancy.Rheumatic diseases clinics of North America · 2025
    Review
  4. Engagement with health research summaries via digital communication to All of Us participants.Journal of the American Medical Informatics Association : JAMIA · 2024
    Article
  5. Article
  6. Article
  7. Community-engaged training in informed consent.Journal of clinical and translational science · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Maria I DanilaDepartment of Medicine, Division of Clinical Immunology/Rheumatology, University of Alabama at Birmingham School of Medicine, Birmingham, AL, USA.
Jeroan J AllisonUMass Center for Clinical and Translational Science, University of Massachusetts Medical School, Worcester, MA, USA.
Karin Valentine GoinsUMass Center for Clinical and Translational Science, University of Massachusetts Medical School, Worcester, MA, USA.
Germán ChiribogaUMass Center for Clinical and Translational Science, University of Massachusetts Medical School, Worcester, MA, USA.
Melissa FischerDepartment of Population and Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA, USA.
Melissa PuliaficoDepartment of Population and Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA, USA.
Amy S MudanoDepartment of Medicine, Division of Clinical Immunology/Rheumatology, University of Alabama at Birmingham School of Medicine, Birmingham, AL, USA.
Elizabeth J RahnDepartment of Medicine, Division of Clinical Immunology/Rheumatology, University of Alabama at Birmingham School of Medicine, Birmingham, AL, USA.
Jeanne MerchantDepartment of Medicine, Division of Clinical Immunology/Rheumatology, University of Alabama at Birmingham School of Medicine, Birmingham, AL, USA.
Colleen E LawrenceVanderbilt Institute for Clinical and Translational Research (VICTR), Vanderbilt University Medical Center, Nashville, TN, USA.
Leah DunkelVanderbilt Institute for Clinical and Translational Research (VICTR), Vanderbilt University Medical Center, Nashville, TN, USA.
Tiffany IsraelVanderbilt Institute for Clinical and Translational Research (VICTR), Vanderbilt University Medical Center, Nashville, TN, USA.ORCID https://orcid.org/0000-0002-0852-8390
Bruce BartonDepartment of Population and Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA, USA.
Fred JenoureUMass Center for Clinical and Translational Science, University of Massachusetts Medical School, Worcester, MA, USA.
Tiffany AlexanderUniversity of Alabama at Birmingham Center for Clinical and Translational Science, University of Alabama at Birmingham School of Medicine, Birmingham, AL, USA.
Danny CruzVanderbilt Institute for Clinical and Translational Research (VICTR), Vanderbilt University Medical Center, Nashville, TN, USA.
Marva DouglasUniversity of Alabama at Birmingham Center for Clinical and Translational Science, University of Alabama at Birmingham School of Medicine, Birmingham, AL, USA.
Jacqueline SimsVanderbilt Institute for Clinical and Translational Research (VICTR), Vanderbilt University Medical Center, Nashville, TN, USA.
Al RichmondCommunity Campus Partnerships for Health, Raleigh, NC, USA.
Erik D RobersonDepartment of Neurology, University of Alabama at Birmingham School of Medicine, Birmingham, AL, USA.
Carol ChamblessDepartment of Neurology, University of Alabama at Birmingham School of Medicine, Birmingham, AL, USA.
Paul A HarrisDepartment of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA.ORCID https://orcid.org/0000-0002-1744-2011
Kenneth G SaagDepartment of Medicine, Division of Clinical Immunology/Rheumatology, University of Alabama at Birmingham School of Medicine, Birmingham, AL, USA.
Stephenie C LemonUMass Center for Clinical and Translational Science, University of Massachusetts Medical School, Worcester, MA, USA.ORCID https://orcid.org/0000-0003-3321-6070

Funding

Vanderbilt Institute for Clinical and Translational Research (VICTR) -Identifying correlates of functional immunity in SARS-CoV-2 convalescent plasmaUL1TR002243 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Paul A. Harris, Wesley H Self · 2017 to 2026
$130.7M
National Dissemination of I-Corps@NCATS: Accelerating Translation through CommercializationUL1TR003096 · NCATS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI GUTIERREZ, ORLANDO M, KIMBERLY, ROBERT P. · 2019 to 2023
$43.6M
University of Massachusetts Center for Clinical Science and Translational SupplementUL1TR001453 · NCATS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI LUZURIAGA, KATHERINE F · 2015 to 2024
$39.0M
Improving Clinical trial Education, Recruitment, and Enrollment at CTSA Hubs (I-CERCH) - HEAL SupplementU24TR001579 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI HARRIS, PAUL A., WILKINS, CONSUELO HOPKINS · 2016 to 2022
$34.1M
UAB Center for Clinical and Translational Science (CCTS)UL1TR001417 · NCATS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI KIMBERLY, ROBERT P. · 2015 to 2018
$31.4M
Strengthening Translational Research in Diverse Enrollment (STRIDE)U01TR001812 · NCATS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI ALLISON, JEROAN J, HARRIS, PAUL A. · 2016 to 2020
$5.0M
UAB Alzheimer's Disease Research CenterP20AG068024 · NIA · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ROBERSON, ERIK D · 2020 to 2022
$3.3M
Training Program for Strengthening Research Capacity in Non-Communicable Diseases in Vietnam (TSORC-NCDs-VN)D43TW011394 · FIC · HANOI MEDICAL UNIVERSITY · PI JEROAN J ALLISON, Dao THI MINH AN · 2019 to 2026
$1.8M
Prevention And Control of Cancer: Training for Change in Individuals and SystemsT32CA172009 · NCI · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI LEMON, STEPHENIE C., OCKENE, JUDITH K · 2019 to 2023
$1.5M
FIC NIH HHS D43 TW011394NCATS NIH HHS U01 TR001812NCATS NIH HHS U24 TR001579NCATS NIH HHS UL1 TR001417NCATS NIH HHS UL1 TR001453NCATS NIH HHS UL1 TR002243NCATS NIH HHS UL1 TR003096NCI NIH HHS T32 CA172009NIA NIH HHS P20 AG068024
6 · The paper itself

Abstract

introductionBarriers to research participation by racial and ethnic minority group members are multi-factorial, stem from historical social injustices and occur at participant, research team, and research process levels. The informed consent procedure is a key component of the research process and represents an opportunity to address these barriers. This manuscript describes the development of the Strengthening Translational Research in Diverse Enrollment (STRIDE) intervention, which aims to improve research participation by individuals from underrepresented groups.

methodsWe used a community-engaged approach to develop an integrated, culturally, and literacy-sensitive, multi-component intervention that addresses barriers to research participation during the informed consent process. This approach involved having Community Investigators participate in intervention development activities and using community engagement studios and other methods to get feedback from community members on intervention components.

resultsThe STRIDE intervention has three components: a simulation-based training program directed toward clinical study research assistants that emphasizes cultural competency and communication skills for assisting in the informed consent process, an electronic consent (eConsent) framework designed to improve health-related research material comprehension and relevance, and a "storytelling" intervention in which prior research participants from diverse backgrounds share their experiences delivered via video vignettes during the consent process.

conclusionsThe community engaged development approach resulted in a multi-component intervention that addresses known barriers to research participation and can be integrated into the consent process of research studies. Results of an ongoing study will determine its effectiveness at increasing diversity among research participants.

Indexed as

eConsenthealth disparitiesinterventionResearch participation

Identifiers

PMID34367678
PMCPMC8327553

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.